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Monday Night Football Sharp Betting Pick & Prediction: Pros Hit Rams vs. 49ers Spread

Rams at 49ers Odds

Rams Odds -3.5
49ers Odds +3.5
Over/Under 50.5
Date Monday, Nov. 15
Time 8:15 p.m. ET
TV ESPN

*Odds as of Monday morning

It’s been one helluva week for the Los Angeles Rams.

After releasing wide receiver Desean Jackson on Nov. 2, the Rams filled that void by signing former Cleveland Browns wide receiver Odell Beckham Jr.

The addition of Beckham was even more important after fellow Los Angeles wide receiver Robert Words suffered a torn ACL in Friday’s practice, ending his season.

While Beckham’s involvement tonight on Monday Night Football is still a bit of a question mark, there’s no denying how money from the market’s most respected bettors is influencing Rams vs. 49ers odds.

Using our PRO betting tools, let’s examine how the pros are playing Rams vs. 49ers on Monday Night Football.

Rams vs. 49ers NFL Betting Prediction


Eighty-two percent of bettors are laying the points with Los Angeles, but sharps are in complete disagreement.

The 49ers opened as 4.5-point underdogs against the Rams at DraftKings Sportsbook and wiseguys are all over San Fran in this matchup.

Action Labs’ Bet Signals, which track and report professional betting action in real-time, are reporting multiple waves of smart money flowing on San Francisco since this number was posted, explaining why the 49ers spread has moved to +3.5 (click here for live NFL odds) across the market.

In addition, two of The Action Network’s top NFL bettors are aligned with the wiseguys by getting down on San Francisco and the points for Monday Night Football.

PRO Projections Pick: 49ers +3.5

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