If you’re in the market for new, savvy ways to make your weekly NFL predictions this season, PRO Systems is the jackpot.
And the action kicks off Sunday, in a big wave.
Three separate NFL betting systems are active with data-driven predictions, combining for nine total picks to consider locking in for the first big slate.
Here are the key Week 1 angles and data points:
- Best Upset Picks
- Undervalued Road Teams
- How to Bet the Windiest Games
All PRO Systems are historically-profitable betting trends. We utilize them to guide us to what’s typically been the right bet to make, under an array of different situations.
Sunday’s Week 1 predictions feature three strategies, and here’s a spoiler: It’s a full package of moneyline, spread, and over/under picks.
Best NFL Week 1 Moneyline Picks
All recommended NFL picks listed first and bolded*
In the spirit of Week 1, let’s open with the best upset picks. Our one and only moneyline system pinged three teams on upset alert to shake up the season right off the bat.
The “Early Season Upsets” PRO System strategy focuses on placing moneyline bets on divisional underdogs within a 0-5.5 spread in the initial three weeks. The strategy banks on the uncertainty of how a team performs early in the season, and the likelihood of upsets due to divisional familiarity.
At the time of writing, three teams check all the boxes for this Sunday of NFL Week 1 to pull off upsets.
- Panthers vs. Saints
- Colts vs. Texans
- Raiders vs. Chargers
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Best NFL Week 1 Spread Picks
Secondly, we transition to four road teams undervalued against the spread Sunday of NFL Week 1.
Our “Road Dog, Low Total After Bad Season” model looks to exploit a belief that a team might not be very good … based on last year’s performance, which often sticks in the minds of public bettors early on.
How do we counter that? Betting underdogs (+6.5 or less) with low totals (50 or under) if they won six or fewer games the year prior.
This angle is good for the first six weeks of the NFL season, cashing 59% lifetime. However, the trend increases to 62% when narrowed down to months of September, November or December.
Four underdogs (all of which underwhelmed last season) are well-suited to cover Sunday of NFL Week 1.
- Titans to cover vs. Bears
- Cardinals to cover vs. Bills
- Panthers to cover vs. Saints
- Commanders to cover vs. Buccaneers
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Best NFL Week 1 Over/Under Picks
The forecast provides some of the best NFL over/under picks for Week 1.
If you’re curious at which point wind becomes a factor in NFL games, or when it becomes influential to betting markets — specifically the over/under how many points are scored — we have the answer to that.
Wind is a revealing, profitable trend on NFL totals when gusts pick up past 10 mph sometimes all the way to 50 mph. These games have landed under 57% of the time since tracking began. We excluded cold games (32 degrees or below) because they tend to go over due to public overreaction.
Two games feature severe (enough) winds on Sunday of Week 1 to bet under the total.
- Cardinals vs. Bills Under
- Cowboys vs. Browns Under
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Our PRO signals flag far more great picks than our staff could author each day — that’s where Action AI comes in. Using generative AI, signals that hit a high grade threshold are written up into articles that are then vetted and edited by a human to help us get you all the sharp action. Read more about how it works here.