NFL Odds, Picks, Predictions for Every Game: Week 5 Schedule

Our experts have taken a look up and down the NFL Week 5 schedule, and they’ve come away with their best bets for every game.

The tightest spread at the moment is in Bills vs. Texans, where the Texans are currently just 1-point favorites over the Bills (Texans -1). The biggest spread is in Cardinals vs. 49ers, as San Francisco is a 7.5-point favorite (49ers -7.5).

The highest over/under on the board at the moment is 49 points, which is the total in both Cardinals vs. 49ers and Packers vs. Rams, while the lowest total is the over/under 36 in both Dolphins vs. Patriots and Raiders vs. Broncos.

But those are just the superlatives. Let’s get to the Week 5 NFL odds, the full schedule, our expert picks, and NFL predictions for every game.

Week 5 NFL Predictions

• Dolphins vs. Patriots Prediction: Under the total
• Panthers vs. Bears Prediction: Panthers to cover the spread
• Colts vs. Jaguars Prediction: Jaguars to cover the spread
• Bills vs. Texans Prediction: Texans to cover the spread
• Ravens vs. Bengals Prediction: Bengals to cover the spread
• Browns vs. Commanders Prediction: Browns to cover the spread
• Raiders vs. Broncos Prediction: Broncos to cover the spread
• Cardinals vs. 49ers Prediction: Cardinals to cover the spread
• Giants vs. Seahawks Prediction: Giants to cover the spread
• Packers vs. Rams Prediction: Rams to cover the spread
• Cowboys vs. Steelers Prediction: Steelers to cover the spread
• Saints vs. Chiefs Prediction: Under the total

NFL Odds, Spreads Today

• Dolphins vs. Patriots Spread: Dolphins -1.5
• Panthers vs. Bears Spread: Bears -4
• Colts vs. Jaguars Spread: Jaguars -3.5
• Bills vs. Texans Spread: Texans -1
• Ravens vs. Bengals Spread: Ravens -2.5
• Browns vs. Commanders Spread: Commanders -3
• Raiders vs. Broncos Spread: Broncos -3
• Cardinals vs. 49ers Spread: 49ers -7.5
• Giants vs. Seahawks Spread: Seahawks -7
• Packers vs. Rams Spread: Packers -3
• Cowboys vs. Steelers Spread: Steelers -2.5
• Saints vs. Chiefs Spread: Chiefs -5.5

Week 5 NFL Schedule

New York Jets at Minnesota Vikings

[gamematchup league=”nfl” awaylogo=”https://assets.actionnetwork.com/372790_jets.png” awayname=”Jets” awayslug=”new-york-jets” homelogo=”https://static.sprtactn.co/teamlogos/nfl/100/min.png” homename=”Vikings” homeslug=”minnesota-vikings” date=”Sunday, Oct 6″ time=”9:30 a.m. ET” network=”NFL Network” col1text=”Spread” col2text=”Total” col3text=”Moneyline” col1awaytext=”+2.5″ col1awayline=”-105″ col1hometext=”-2.5″ col1homeline=”-115″ col2awaytext=”41.5″ col2hometext=”41.5″ col2awayline=”-108o / -112u” col2homeline=”-108o / -112u” col3awaytext=”+124″ col3hometext=”-135″ col3awayline=”” col3homeline=”” bookname=”DraftKings” bookthumbnaillogo=”https://assets.actionnetwork.com/603379_Primary.png” bookreviewslug=”draftkings”][/gamematchup]

• Jets vs. Vikings Spread: Vikings -2.5
• Jets vs. Vikings Over/Under: 41.5 points
• Jets vs. Vikings Moneyline: Vikings -145, Jets +120
• Jets vs. Vikings Pick, Prediction: Jets to cover the spread

Miami Dolphins at New England Patriots

[gamematchup league=”nfl” awaylogo=”https://static.sprtactn.co/teamlogos/nfl/100/mia.png” awayname=”Dolphins” awayslug=”miami-dolphins” homelogo=”https://static.sprtactn.co/teamlogos/nfl/100/ne.png” homename=”Patriots” homeslug=”new-england-patriots” date=”Sunday, Oct 6″ time=”1 p.m. ET” network=”FOX” col1text=”Spread” col2text=”Total” col3text=”Moneyline” col1awaytext=”-1″ col1awayline=”-112″ col1hometext=”+1″ col1homeline=”-108″ col2awaytext=”35.5″ col2hometext=”35.5″ col2awayline=”-108o / -112u” col2homeline=”-108o / -112u” col3awaytext=”-115″ col3hometext=”+100″ col3awayline=”” col3homeline=”” bookname=”DraftKings” bookthumbnaillogo=”https://assets.actionnetwork.com/603379_Primary.png” bookreviewslug=”draftkings”][/gamematchup]

• Dolphins vs. Patriots Spread: Dolphins -1
• Dolphins vs. Patriots Over/Under: 35.5 points
• Dolphins vs. Patriots Moneyline: Dolphins -118, Patriots -102
• Dolphins vs. Patriots Pick, Prediction: Under the total

Carolina Panthers at Chicago Bears

[gamematchup league=”nfl” awaylogo=”https://static.sprtactn.co/teamlogos/nfl/100/car.png” awayname=”Panthers” awayslug=”carolina-panthers” homelogo=”https://assets.actionnetwork.com/598430_bears1.png” homename=”Bears” homeslug=”chicago-bears” date=”Sunday, Oct 6″ time=”1 p.m. ET” network=”FOX” col1text=”Spread” col2text=”Total” col3text=”Moneyline” col1awaytext=”+4″ col1awayline=”-110″ col1hometext=”-4″ col1homeline=”-110″ col2awaytext=”41″ col2hometext=”41″ col2awayline=”-108o / -112u” col2homeline=”-108o / -112u” col3awaytext=”+155″ col3hometext=”-180″ col3awayline=”” col3homeline=”” bookname=”DraftKings” bookthumbnaillogo=”https://assets.actionnetwork.com/603379_Primary.png” bookreviewslug=”draftkings”][/gamematchup]

• Panthers vs. Bears Spread: Bears -4
• Panthers vs. Bears Over/Under: 41 points
• Panthers vs. Bears Moneyline: Bears -200, Panthers +165
• Panthers vs. Bears Pick, Prediction: Panthers to cover the spread

Indianapolis Colts at Jacksonville Jaguars

[gamematchup league=”nfl” awaylogo=”https://static.sprtactn.co/teamlogos/nfl/100/ind.png” awayname=”Colts” awayslug=”indianapolis-colts” homelogo=”https://static.sprtactn.co/teamlogos/nfl/100/jac.png” homename=”Jaguars” homeslug=”jacksonville-jaguars” date=”Sunday, Oct 6″ time=”1 p.m. ET” network=”CBS” col1text=”Spread” col2text=”Total” col3text=”Moneyline” col1awaytext=”+3.5″ col1awayline=”-118″ col1hometext=”-3.5″ col1homeline=”-102″ col2awaytext=”45″ col2hometext=”45″ col2awayline=”-112o / -108u” col2homeline=”-112o / -108u” col3awaytext=”+142″ col3hometext=”-165″ col3awayline=”” col3homeline=”” bookname=”DraftKings” bookthumbnaillogo=”https://assets.actionnetwork.com/603379_Primary.png” bookreviewslug=”draftkings”][/gamematchup]

• Colts vs. Jaguars Spread: Jaguars -3.5
• Colts vs. Jaguars Over/Under: 45.5 points
• Colts vs. Jaguars Moneyline: Jaguars -175, Colts +145
• Colts vs. Jaguars Pick, Prediction: Jaguars to cover the spread

Buffalo Bills at Houston Texans

[gamematchup league=”nfl” awaylogo=”https://static.sprtactn.co/teamlogos/nfl/100/buf.png” awayname=”Bills” awayslug=”buffalo-bills” homelogo=”https://static.sprtactn.co/teamlogos/nfl/100/hou.png” homename=”Texans” homeslug=”houston-texans” date=”Sunday, Oct 6″ time=”1 p.m. ET” network=”CBS” col1text=”Spread” col2text=”Total” col3text=”Moneyline” col1awaytext=”+1″ col1awayline=”-110″ col1hometext=”-1″ col1homeline=”-110″ col2awaytext=”47″ col2hometext=”47″ col2awayline=”-108o / -112u” col2homeline=”-108o / -112u” col3awaytext=”+100″ col3hometext=”-115″ col3awayline=”” col3homeline=”” bookname=”DraftKings” bookthumbnaillogo=”https://assets.actionnetwork.com/603379_Primary.png” bookreviewslug=”draftkings”][/gamematchup]

• Bills vs. Texans Spread: Texans -1
• Bills vs. Texans Over/Under: 47 points
• Bills vs. Texans Moneyline: Texans -120, Bills +100
• Bills vs. Texans Pick, Prediction: Texans to cover the spread

Baltimore Ravens at Cincinnati Bengals

[gamematchup league=”nfl” awaylogo=”https://static.sprtactn.co/teamlogos/nfl/100/bal.png” awayname=”Ravens” awayslug=”baltimore-ravens” homelogo=”https://static.sprtactn.co/teamlogos/nfl/100/cin.png” homename=”Bengals” homeslug=”cincinnati-bengals” date=”Sunday, Oct 6″ time=”1 p.m. ET” network=”CBS” col1text=”Spread” col2text=”Total” col3text=”Moneyline” col1awaytext=”-2.5″ col1awayline=”-108″ col1hometext=”+2.5″ col1homeline=”-112″ col2awaytext=”48.5″ col2hometext=”48.5″ col2awayline=”-110o / -110u” col2homeline=”-110o / -110u” col3awaytext=”-130″ col3hometext=”+115″ col3awayline=”” col3homeline=”” bookname=”DraftKings” bookthumbnaillogo=”https://assets.actionnetwork.com/603379_Primary.png” bookreviewslug=”draftkings”][/gamematchup]

• Ravens vs. Bengals Spread: Ravens -2.5
• Ravens vs. Bengals Over/Under: 48.5 points
• Ravens vs. Bengals Moneyline: Ravens -135, Bengals +115
• Ravens vs. Bengals Pick, Prediction: Bengals to cover the spread

Cleveland Browns at Washington Commanders

[gamematchup league=”nfl” awaylogo=”https://assets.actionnetwork.com/519602_browns.png” awayname=”Browns” awayslug=”cleveland-browns” homelogo=”https://assets.actionnetwork.com/698864_Commanders.png” homename=”Commanders” homeslug=”washington-commanders” date=”Sunday, Oct 6″ time=”1 p.m. ET” network=”FOX” col1text=”Spread” col2text=”Total” col3text=”Moneyline” col1awaytext=”+3″ col1awayline=”-115″ col1hometext=”-3″ col1homeline=”-105″ col2awaytext=”43.5″ col2hometext=”43.5″ col2awayline=”-112o / -108u” col2homeline=”-112o / -108u” col3awaytext=”+125″ col3hometext=”-145″ col3awayline=”” col3homeline=”” bookname=”DraftKings” bookthumbnaillogo=”https://assets.actionnetwork.com/603379_Primary.png” bookreviewslug=”draftkings”][/gamematchup]

• Browns vs. Commanders Spread: Commanders -3
• Browns vs. Commanders Over/Under: 43.5 points
• Browns vs. Commanders Moneyline: Commanders -150, Browns +125
• Browns vs. Commanders Pick, Prediction: Browns to cover the spread

Las Vegas Raiders at Denver Broncos

[gamematchup league=”nfl” awaylogo=”https://static.sprtactn.co/teamlogos/nfl/100/oak.png” awayname=”Raiders” awayslug=”las-vegas-raiders” homelogo=”https://static.sprtactn.co/teamlogos/nfl/100/den.png” homename=”Broncos” homeslug=”denver-broncos” date=”Sunday, Oct 6″ time=”4:05 p.m. ET” network=”FOX” col1text=”Spread” col2text=”Total” col3text=”Moneyline” col1awaytext=”+2.5″ col1awayline=”+100″ col1hometext=”-2.5″ col1homeline=”-120″ col2awaytext=”35.5″ col2hometext=”35.5″ col2awayline=”-108o / -112u” col2homeline=”-108o / -112u” col3awaytext=”+124″ col3hometext=”-140″ col3awayline=”” col3homeline=”” bookname=”DraftKings” bookthumbnaillogo=”https://assets.actionnetwork.com/603379_Primary.png” bookreviewslug=”draftkings”][/gamematchup]

• Raiders vs. Broncos Spread: Broncos -2.5
• Raiders vs. Broncos Over/Under: 35.5 points
• Raiders vs. Broncos Moneyline: Broncos -150, Raiders +125
• Raiders vs. Broncos Pick, Prediction: Broncos to cover the spread

Arizona Cardinals at San Francisco 49ers

[gamematchup league=”nfl” awaylogo=”https://static.sprtactn.co/teamlogos/nfl/100/ari.png” awayname=”Cardinals” awayslug=”arizona-cardinals” homelogo=”https://static.sprtactn.co/teamlogos/nfl/100/sf.png” homename=”49ers” homeslug=”san-francisco-49ers” date=”Sunday, Oct 6″ time=”4:05 p.m. ET” network=”FOX” col1text=”Spread” col2text=”Total” col3text=”Moneyline” col1awaytext=”+7″ col1awayline=”-108″ col1hometext=”-7″ col1homeline=”-112″ col2awaytext=”48.5″ col2hometext=”48.5″ col2awayline=”-110o / -110u” col2homeline=”-110o / -110u” col3awaytext=”+280″ col3hometext=”-330″ col3awayline=”” col3homeline=”” bookname=”DraftKings” bookthumbnaillogo=”https://assets.actionnetwork.com/603379_Primary.png” bookreviewslug=”draftkings”][/gamematchup]

• Cardinals vs. 49ers Spread: 49ers -7
• Cardinals vs. 49ers Over/Under: 49 points
• Cardinals vs. 49ers Moneyline: 49ers -350, Cardinals +275
• Cardinals vs. 49ers Pick, Prediction: Cardinals to cover the spread

New York Giants at Seattle Seahawks

[gamematchup league=”nfl” awaylogo=”https://static.sprtactn.co/teamlogos/nfl/100/nygd.png” awayname=”Giants” awayslug=”new-york-giants” homelogo=”https://static.sprtactn.co/teamlogos/nfl/100/sea.png” homename=”Seahawks” homeslug=”seattle-seahawks” date=”Sunday, Oct 6″ time=”4:25 p.m. ET” network=”CBS” col1text=”Spread” col2text=”Total” col3text=”Moneyline” col1awaytext=”+7″ col1awayline=”-110″ col1hometext=”-7″ col1homeline=”-110″ col2awaytext=”42.5″ col2hometext=”42.5″ col2awayline=”-112o / -108u” col2homeline=”-112o / -108u” col3awaytext=”+270″ col3hometext=”-320″ col3awayline=”” col3homeline=”” bookname=”DraftKings” bookthumbnaillogo=”https://assets.actionnetwork.com/603379_Primary.png” bookreviewslug=”draftkings”][/gamematchup]

• Giants vs. Seahawks Spread: Seahawks -7
• Giants vs. Seahawks Over/Under: 42.5 points
• Giants vs. Seahawks Moneyline: Seahawks -330, Giants +265
• Giants vs. Seahawks Pick, Prediction: Giants to cover the spread

Green Bay Packers at Los Angeles Rams

[gamematchup league=”nfl” awaylogo=”https://static.sprtactn.co/teamlogos/nfl/100/gb.png” awayname=”Packers” awayslug=”green-bay-packers” homelogo=”https://static.sprtactn.co/teamlogos/nfl/100/la.png” homename=”Rams” homeslug=”los-angeles-rams” date=”Sunday, Oct 6″ time=”4:25 p.m. ET” network=”CBS” col1text=”Spread” col2text=”Total” col3text=”Moneyline” col1awaytext=”-3″ col1awayline=”-120″ col1hometext=”+3″ col1homeline=”+100″ col2awaytext=”49″ col2hometext=”49″ col2awayline=”-110o / -110u” col2homeline=”-110o / -110u” col3awaytext=”-162″ col3hometext=”+140″ col3awayline=”” col3homeline=”” bookname=”DraftKings” bookthumbnaillogo=”https://assets.actionnetwork.com/603379_Primary.png” bookreviewslug=”draftkings”][/gamematchup]

• Packers vs. Rams Spread: Packers -3
• Packers vs. Rams Over/Under: 49 points
• Packers vs. Rams Moneyline: Packers -165, Rams +140
• Packers vs. Rams Pick, Prediction: Rams to cover the spread

Sunday Night Football: Dallas Cowboys at Pittsburgh Steelers

[gamematchup league=”nfl” awaylogo=”https://static.sprtactn.co/teamlogos/nfl/100/dal.png” awayname=”Cowboys” awayslug=”dallas-cowboys” homelogo=”https://static.sprtactn.co/teamlogos/nfl/100/pit.png” homename=”Steelers” homeslug=”pittsburgh-steelers” date=”Sunday, Oct 6″ time=”8:20 p.m. ET” network=”NBC” col1text=”Spread” col2text=”Total” col3text=”Moneyline” col1awaytext=”+3″ col1awayline=”-115″ col1hometext=”-3″ col1homeline=”-105″ col2awaytext=”44″ col2hometext=”44″ col2awayline=”-108o / -112u” col2homeline=”-108o / -112u” col3awaytext=”+125″ col3hometext=”-145″ col3awayline=”” col3homeline=”” bookname=”DraftKings” bookthumbnaillogo=”https://assets.actionnetwork.com/603379_Primary.png” bookreviewslug=”draftkings”][/gamematchup]

• Cowboys vs. Steelers Spread: Steelers -2.5
• Cowboys vs. Steelers Over/Under: 44 points
• Cowboys vs. Steelers Moneyline: Steelers -150, Cowboys +125
• Cowboys vs. Steelers Pick, Prediction: Steelers to cover the spread

Monday Night Football: New Orleans Saints at Kansas City Chiefs

[gamematchup league=”nfl” awaylogo=”https://static.sprtactn.co/teamlogos/nfl/100/no.png” awayname=”Saints” awayslug=”new-orleans-saints” homelogo=”https://static.sprtactn.co/teamlogos/nfl/100/kc.png” homename=”Chiefs” homeslug=”kansas-city-chiefs” date=”Monday, Oct 7″ time=”8:15 p.m. ET” network=”ESPN” col1text=”Spread” col2text=”Total” col3text=”Moneyline” col1awaytext=”+5.5″ col1awayline=”-108″ col1hometext=”-5.5″ col1homeline=”-112″ col2awaytext=”43″ col2hometext=”43″ col2awayline=”-112o / -108u” col2homeline=”-112o / -108u” col3awaytext=”+210″ col3hometext=”-245″ col3awayline=”” col3homeline=”” bookname=”DraftKings” bookthumbnaillogo=”https://assets.actionnetwork.com/603379_Primary.png” bookreviewslug=”draftkings”][/gamematchup]

• Saints vs. Chiefs Spread: Chiefs -5.5
• Cowboys vs. Steelers Over/Under: 43 points
• Cowboys vs. Steelers Moneyline: Chiefs -250, Saints +200
• Saints vs. Chiefs Pick, Prediction: Under the total