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NFL Odds, Picks, Predictions for Every Game: Week 4 NFL Schedule

Our experts have taken a look up and down the NFL Week 4 schedule, and they’ve come away with their best bets for every game.

The tightest spread at the moment is in Eagles vs. Buccaneers, where the Eagles are currently just 1-point favorites (-1) over the Bucs. The biggest spread is in Patriots vs. 49ers, as San Francisco is a 10.5-point favorite (-10.5) against New England. The highest over/under is in Commanders vs. Cardinals at 48.5 points, and the lowest total is the over/under 37 in both Browns vs. Raiders and Titans vs. Dolphins.

But those are just the superlatives. Let’s get to the Week 4 NFL odds, our expert picks, and NFL predictions for every game.

Week 4 NFL Predictions

NFL Odds, Spreads Today

  • Broncos vs. Jets Spread: Jets -8
  • Bengals vs. Panthers Spread: Bengals -4.5
  • Eagles vs. Buccaneers Spread: Eagles -1
  • Rams vs. Bears Spread: Bears -3
  • Saints vs. Falcons Spread: Falcons -2.5
  • Jaguars vs. Texans Spread: Texans -5.5
  • Vikings vs. Packers Spread: Packers -2.5
  • Steelers vs. Colts Spread: Steelers -2.5
  • Patriots vs. 49ers Spread: 49ers -10.5
  • Commanders vs. Cardinals Spread: Cardinals -3.5
  • Chiefs vs. Chargers Spread: Chiefs -7.5
  • Browns vs. Raiders Spread: Browns -2.5
  • Bills vs. Ravens Spread: Ravens -2.5
  • Titans vs. Dolphins Spread: Dolphins -2.5
  • Seahawks vs. Lions Spread: Lions -3.5

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Week 4 NFL Schedule

Denver Broncos at New York Jets

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  • Broncos vs. Jets Spread: Jets -8
  • Broncos vs. Jets Over/Under: 39.5 points
  • Broncos vs. Jets Moneyline: Jets -425, Broncos +325
  • Broncos vs. Jets Pick, Prediction: Garrett Wilson player prop

Cincinnati Bengals at Carolina Panthers

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  • Bengals vs. Panthers Spread: Bengals -4.5
  • Bengals vs. Panthers Over/Under: 47 points
  • Bengals vs. Panthers Moneyline: Bengals -210, Panthers +180
  • Bengals vs. Panthers Pick, Prediction: Bengals to cover the spread

Philadelphia Eagles at Tampa Bay Buccaneers

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  • Eagles vs. Buccaneers Spread: Eagles -1
  • Eagles vs. Buccaneers Over/Under: 42
  • Eagles vs. Buccaneers Moneyline: Eagles -121, Bucs +100
  • Eagles vs. Buccaneers Pick, Prediction: Bucs to cover the spread

Los Angeles Rams at Chicago Bears

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  • Rams vs. Bears Spread: Bears -3
  • Rams vs. Bears Over/Under: 40.5 points
  • Rams vs. Bears Moneyline: Bears -160, Rams +135
  • Rams vs. Bears Pick, Prediction: Bears to cover the spread

New Orleans Saints at Atlanta Falcons

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  • Saints vs. Falcons Spread: Falcons -2.5
  • Saints vs. Falcons Over/Under: 41.5 points
  • Saints vs. Falcons Moneyline: Falcons -141, Saints +120
  • Saints vs. Falcons Pick, Prediction: Falcons to cover the spread

Jacksonville Jaguars at Houston Texans

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  • Jaguars vs. Texans Spread: Texans -5.5
  • Jaguars vs. Texans Over/Under: 44.5 points
  • Jaguars vs. Texans Moneyline: Texans -225, Jaguars +190
  • Jaguars vs. Texans Pick, Prediction: Jaguars to cover the spread

Minnesota Vikings at Green Bay Packers

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  • Vikings vs. Packers Spread: Packers -3
  • Vikings vs. Packers Over/Under: 44 points
  • Vikings vs. Packers Moneyline: Packers -145, Vikings +120
  • Vikings vs. Packers Pick, Prediction: Vikings to cover the spread

Pittsburgh Steelers at Indianapolis Colts

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  • Steelers vs. Colts Spread: Steelers -2.5
  • Steelers vs. Colts Over/Under: 40 points
  • Steelers vs. Colts Moneyline: Steelers -130, Colts +110
  • Steelers vs. Colts Pick, Prediction: Colts to cover the spread

New England Patriots at San Francisco 49ers

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  • Patriots vs. 49ers Spread: 49ers -10.5
  • Patriots vs. 49ers Over/Under: 41.5 points
  • Patriots vs. 49ers Moneyline: 49ers -500, Patriots +400
  • Patriots vs. 49ers Pick, Prediction: Patriots to cover the spread

Washington Commanders at Arizona Cardinals

[gamematchup league=”nfl” awaylogo=”https://assets.actionnetwork.com/698864_Commanders.png” awayname=”Commanders” awayslug=”washington-commanders” homelogo=”https://static.sprtactn.co/teamlogos/nfl/100/ari.png” homename=”Cardinals” homeslug=”arizona-cardinals” date=”Sunday, Sep 29″ time=”4:05 p.m. ET” network=”FOX” col1text=”Spread” col2text=”Total” col3text=”Moneyline” col1awaytext=”+3.5″ col1awayline=”-118″ col1hometext=”-3.5″ col1homeline=”-102″ col2awaytext=”49″ col2hometext=”49″ col2awayline=”-110o / -110u” col2homeline=”-110o / -110u” col3awaytext=”+150″ col3hometext=”-175″ col3awayline=”” col3homeline=”” bookname=”DraftKings” bookthumbnaillogo=”https://assets.actionnetwork.com/603379_Primary.png” bookreviewslug=”draftkings”][/gamematchup]

  • Commanders vs. Cardinals Spread: Cardinals -3.5
  • Commanders vs. Cardinals Over/Under: 48.5 points
  • Commanders vs. Cardinals Moneyline: Cardinals -175, Commanders +150
  • Commanders vs. Cardinals Pick, Prediction: Cardinals to cover the spread

Kansas City Chiefs at Los Angeles Chargers

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  • Chiefs vs. Chargers Spread: Chiefs -7.5
  • Chiefs vs. Chargers Over/Under: 41.5 points
  • Chiefs vs. Chargers Moneyline: Chiefs -350, Chargers +300
  • Chiefs vs. Chargers Pick, Prediction: Chargers to cover the 1H spread

Cleveland Browns at Las Vegas Raiders

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  • Browns vs. Raiders Spread: Browns -2.5
  • Browns vs. Raiders Over/Under: 37 points
  • Browns vs. Raiders Moneyline: Browns -140, Raiders +120
  • Browns vs. Raiders Pick, Prediction: Raiders to cover the spread

Sunday Night Football: Buffalo Bills at Baltimore Ravens

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  • Bills vs. Ravens Spread: Ravens -2.5
  • Bills vs. Ravens Over/Under: 46.5 points
  • Bills vs. Ravens Moneyline: Ravens -135, Bills +115
  • Bills vs. Ravens Pick, Prediction: Ravens to cover the spread

Monday Night Football Doubleheader: Tennessee Titans at Miami Dolphins

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  • Titans vs. Dolphins Spread: Dolphins -2.5
  • Titans vs. Dolphins Over/Under: 37 points
  • Titans vs. Dolphins Moneyline: Dolphins -135, Titans +115
  • Titans vs. Dolphins Pick, Prediction: Under the total

Monday Night Football Doubleheader: Seattle Seahawks at Detroit Lions

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  • Seahawks vs. Lions Spread: Lions -3.5
  • Seahawks vs. Lions Over/Under: 46.5 points
  • Seahawks vs. Lions Moneyline: Lions -185, Seahawks +160
  • Seahawks vs. Lions Pick, Prediction: Under the Lions team total

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