49ers vs. Cardinals Odds
| 49ers Odds | -9 |
| Cardinals Odds | +9 |
| Over/Under | 43 |
| Date | Monday, Nov. 21 |
| Time | 8:15 p.m. ET |
| Channel | ESPN |
*Odds as of Monday morning
NFL Week 11 concludes with the San Francisco 49ers taking on the Arizona Cardinals on Monday Night Football in Mexico City.
According to NFL Network’s Ian Rapoport, Kyler Murray’s injured hamstring is expected to sideline him tonight, paving the way for backup quarterback Colt McCoy to start for Arizona on Monday Night Football.
This appears to be reflected in the latest NFL odds for 49ers vs. Cardinals, evidenced by the 8.5-point spread.
With McCoy under center, tonight’s game may not be as competitive as it would have been, at least on paper, if Murray were healthy, but as NFL bettors all we care about is value.
And according to the Action Network’s NFL picks and predictions, experts are dropping big bucks on a betting model edge for 49ers vs. Cardinals on Monday Night Football.
Let’s take a look.
49ers vs. Cardinals Pick
Arizona may be a big underdog with a backup quarterback getting the start, but that’s the side of tonight’s game showing the most value.
According to our NFL public betting data, the Cards are landing 66% of the money wagered on this spread thus far, but just 44% of the tickets.
This tells us that the larger-sized wagers are taking the points on Monday Night Football.
In addition, the Action Network’s NFL PRO Projections set tonight’s spread at Arizona +7, resulting in a 2.5% edge when compared to the latest spread of Cardinals +9.
And finally, one of our top NFL bettors is on the underdogs as well, providing one more reason to like Arizona in tonight’s Monday Night Football matchup.
While the consensus spread now sits at Cards +9, FanDuel Sportsbook is offering a half-point better at +9.5, so, as always, be sure to shop for the best line before getting down on this Monday Night Football matchup.
PRO Report Pick: Cardinals +9.5
_InlineAdBlock