As we gear up for Week 6 of the college football season, all eyes are on Ohio State as it prepares for its biggest game of the season.
Head coach Ryan Day and the Buckeyes are set to make their Big Ten home debut against Iowa this Saturday. The 3:30 p.m. ET kick is drawing significant attention in the betting markets.
Notably, bettors seem to be heavily favoring one side to cover the spread. According to a 60% trend in our PRO Systems, this could be a game-changer for savvy bettors looking to capitalize on Ohio State football odds.
Ohio State Buckeyes Football Odds Week 6
In terms of the odds, Ohio State is favored by 18.5 points over Iowa.
This is notably the shortest spread of the year for the Buckeyes, who have been favored by 23.5 points or more in every other game this season.
The tighter odds suggest a more competitive matchup, providing an intriguing angle for those analyzing Ohio State football odds.
Ohio State Pick Saturday
On Saturday, betting Iowa to cover may be a smart play.
Our PRO System — dubbed “Road Streak” — highlights a niche trend where Power 4 teams competing in their second (or more) consecutive road game often experience a public fade due to perceived “fatigue.”
Despite this perception, these teams cover the spread 60% of the time under the right conditions. Iowa is coming off a bye week and positioned as the underdog in this high-stakes game against one of the nation’s top teams.
However, historical trends and betting patterns suggest Iowa shouldn’t be underestimated, making them a compelling option for those looking at Ohio State football odds this weekend.
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