Notre Dame has been a mixed bag so far this season, and the Fighting Irish’s football odds are once again in the spotlight as they prepare for a crucial matchup against undefeated Louisville this Saturday in Week 5 on Peacock.
Both teams are ranked — Louisville at 15 and Notre Dame at 16 — setting the stage for a marquee showdown in South Bend on Saturday. After bouncing back from an upset a few weeks ago, Notre Dame has secured back-to-back wins, positioning them well for this clash.
Our premium betting trends indicate an excellent betting strategy for games involving ranked teams, providing valuable insights for this pivotal matchup and how the outcome for Cardinals vs. Fighting Irish may pan out.
Notre Dame Fighting Irish Odds
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The Fighting Irish are favored by -6 to -6.5 points, with the over/under set at 47.5.
Louisville has been impressive this season under head coach Jeff Brohm, going 3-0 against the spread.
Notre Dame Pick for Week 5
We have a plethora of PRO Systems that highlight situational spots to make picks. One such system has nailed 58% of past predictions.
According to our “Ranked Matchups” PRO System, betting on the home team when two Top 25 college football teams face off and the home team is favored by at least 3 points has historically covered the spread 58% of the time since we began tracking.
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In this instance, Notre Dame fits the criteria, making them a strong pick to perhaps crush market expectations and win by more than a touchdown.
Plus, according to Action Network researcher Evan Abrams, Notre Dame is 23-14-1 ATS after a win by 20 or more points, which the Fighting Irish achieved last week against MAC squad Miami (OH).
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