college-football-moneyline-spread-picks-week 6

College Football Moneyline and Spread Picks for Week 6

PRO Projections are live for college football Week 6. And speaking of six…

Three college football games Saturday are so off from our odds, every matchup features the wrong team favored.

Therefore, we’ll cover a grand total of six predictions for Week 6: Moneyline and spread picks for all three games with grade-A ratings.

Moreover, key numbers come into play when comparing our expert projections to the betting markets.

The top Week 6 predictions run all day. Let’s take advantage of some soft college football lines utilizing Action PRO models for Saturday’s slate.


College Football Moneyline and Spread Picks for Week 6

Pitt vs. UNC Predictions Saturday

Pitt is perfect against the spread this season.

UNC, meanwhile, has not covered a single line all year.

Pitt is favored on the road Saturday in Chapel Hill, but a closer look at PRO Report uncovers significant value in backing the Tar Heels.

First, our advanced NCAAF power ratings make UNC (+128) the theoretical favorite with a moneyline of -116, deviating considerably from the current odds. This discrepancy signals a strong betting edge for those eyeing the Tar Heels to pull off the upset.

UNC not only should be a slight favorite on the moneyline but is also a standout pick against the spread. Our power ratings suggest a spread of UNC -1.8 instead of the provided +3, indicating a substantial advantage for bettors taking Carolina with the points.

Pitt vs. UNC PRO Predictions: UNC Moneyline and Spread


UCF vs. Florida Predictions Saturday

The UCF hype train was derailed by Shedeur Sanders and Colorado last week. Taking their first L of the season, the Knights play SEC foe and in-state opponent Florida.

Focusing on the odds, UCF is stationed as a -2.5 point favorite. Current moneyline prices set UCF at -145 and Florida as a +120 underdog.

However, such odds only tell half the story.

There’s a compelling case built by insights from PRO Report to back Florida to upset UCF. Our NCAAF power ratings project the Gators not as slight underdogs, but actually make Billy Napier’s club a -2 favorite, suggesting a misalignment in the market and unlocking an edge for spread and moneyline bettors siding with Florida.

Support for Florida is further bolstered by what the numbers tell us. A significant 66% of the money has backed the Gators, with only 33% of the total bets — which typically indicates the presence of sharp money.

UCF vs. Florida PRO Predictions: Florida Moneyline and Spread


Kansas vs. Arizona State Predictions Saturday

Finally, we turn our attention to a Big 12 clash.

The Sun Devils are favored at home with moneyline odds of -155 and a spread of -3. Meanwhile, the Jayhawks are plus +130 and a spread of +3.

According to our PRO Projections, Kansas holds a significant edge, as our NCAAF power ratings suggest the correct spread should actually favor the Jayhawks by 1.7 points. This projection starkly contrasts the general market and signals a high-value opportunity in the late-window.

Notably, Kansas is also supported by the “Small Visiting Dog (PRO)” system, a historically profitable betting trend with a 51% win rate and a 15% ROI. This adds weight to the argument that taking a position on Kansas offers strong, data-driven backing.

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Kansas vs. Arizona State PRO Predictions: Kansas Moneyline and Spread


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Our PRO signals flag far more great picks than our staff could author each day — that’s where Action AI comes in. Using generative AI, signals that hit a high grade threshold are written up into articles that are then vetted and edited by a human to help us get you all the sharp action. Read more about how it works here.