upset-picks-college-football-week-4-Travis Hunter #12 and Shedeur Sanders #2 of the Colorado Buffaloes

Best College Football Upset Picks for Saturday Week 4

PRO Systems upset-minded NCAAF model is 9-3 this season picking underdogs. Seven more college football upset picks for Saturday Week 4 were flagged.

This isn’t just about throwing darts and longshots and hoping they win; there’s a method to how the PRO System submits college football upset picks.

This angle pops up whenever certain games meet the appropriate spread range, over/under placement, and more.

Early in the season is prime time to capitalize on trends when team strengths remain less predictable.

Based on foolproof data, these are your best bets for pulling off an upset in Week 4 of college football.


Best College Football Upset Picks for Saturday Week 4

The seven picks are the most recommended by the PRO System of any week so far this college football season – a good time to get on board!

And we know just how to spot the best-upset predictions for Week 4.

When a visiting team is +4 or less against the spread and the over/under is 46 or higher, there’s value in betting the underdog to win outright.

Projected high-scoring games tend to produce more variance, increasing the likelihood of moneyline underdogs securing the outright win.

The “Small Visiting Dogs” PRO System has won 75% of games this season. It’s active all over the board Saturday, which features a plethora of tight spreads and high totals.

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At the time of writing, these seven moneyline sides (bolded, listed first) check the boxes for college football Week 4 to upset their opponents.

  • Kansas vs. West Virginia
  • Houston vs. Cincinnati
  • Arizona State vs. Texas Tech
  • Arkansas vs. Auburn
  • FAU vs. UConn
  • Tulsa vs. Louisiana Tech
  • Baylor vs. Colorado

Kansas vs. West Virginia and Houston vs. Cincinnati (12 p.m. ET) are the first two games up.

Baylor vs. Colorado, meanwhile, rounds out the six-game card (8 p.m. ET).

At the time of writing, the best moneyline payouts and biggest upset picks are Houston (+145) and Tulsa (+140).

Shop our college football odds page to view up-to-date prices.


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