The first weekend of March Madness is complete. And after a few days off, we’ll move into the Sweet 16 on Thursday and Friday.
But you don’t have to wait to start breaking down the Sweet 16 odds and Sweet 16 predictions. Here are the odds and our betting expert’s predictions for the point spread, total and final score for every game.
You’ll also find a running tracker of all of our expert picks for each Sweet 16 game based on the latest 2024 March Madness odds.
Sweet 16 Odds, Lines, Spreads, Predictions for Every Game
| Game | Odds, Spread | Prediction |
|---|---|---|
| [teammatchup link=”#1″ followlink=”false” shadow=”false” firstfullname=”Clemson Tigers” firstlogo=”https://static.sprtactn.co/teamlogos/ncaab/100/cle.png” secondfullname=”Arizona Wildcats” secondlogo=”https://static.sprtactn.co/teamlogos/ncaab/100/ari.png” text=”Clemson vs Arizona”][/teammatchup] | Arizona -7 | |
| [teammatchup link=”#2″ followlink=”false” shadow=”false” firstfullname=”San Diego State Aztecs” firstlogo=”https://static.sprtactn.co/teamlogos/ncaab/100/sdsu.png” secondfullname=”Connecticut Huskies” secondlogo=”https://static.sprtactn.co/teamlogos/ncaab/100/uconn.png” text=”San Diego State vs UConn”][/teammatchup] | UConn -10 | |
| [teammatchup link=”#3″ followlink=”false” shadow=”false” firstfullname=”Alabama Crimson Tide” firstlogo=”https://static.sprtactn.co/teamlogos/ncaab/100/bama.png” secondfullname=”North Carolina Tar Heels” secondlogo=”https://static.sprtactn.co/teamlogos/ncaab/100/nc.png” text=”Alabama vs North Carolina”][/teammatchup] | UNC -4 | |
| [teammatchup link=”#4″ followlink=”false” shadow=”false” firstfullname=”Illinois Fighting Illini” firstlogo=”https://static.sprtactn.co/teamlogos/ncaab/100/ill.png” secondfullname=”Iowa State Cyclones” secondlogo=”https://static.sprtactn.co/teamlogos/ncaab/100/isu.png” text=”Illinois vs Iowa State”][/teammatchup] | Iowa State -2.5 | |
| [teammatchup link=”#5″ followlink=”false” shadow=”false” firstfullname=”North Carolina State Wolfpack” firstlogo=”https://static.sprtactn.co/teamlogos/ncaab/100/ncst.png” secondfullname=”Marquette Golden Eagles” secondlogo=”https://static.sprtactn.co/teamlogos/ncaab/100/marq.png” text=”NC State vs Marquette”][/teammatchup] | Marquette -6.5 | |
| [teammatchup link=”#6″ followlink=”false” shadow=”false” firstfullname=”Gonzaga Bulldogs” firstlogo=”https://static.sprtactn.co/teamlogos/ncaab/100/gonz.png” secondfullname=”Purdue Boilermakers” secondlogo=”https://static.sprtactn.co/teamlogos/ncaab/100/pur.png” text=”Gonzaga vs Purdue”][/teammatchup] | Purdue -4.5 | |
| [teammatchup link=”#7″ followlink=”false” shadow=”false” firstfullname=”Duke Blue Devils” firstlogo=”https://static.sprtactn.co/teamlogos/ncaab/100/dukd.png” secondfullname=”Houston Cougars” secondlogo=”https://static.sprtactn.co/teamlogos/ncaab/100/hou.png” text=”Duke vs Houston”][/teammatchup] | Houston -3.5 | |
| [teammatchup link=”#8″ followlink=”false” shadow=”false” firstfullname=”Creighton Bluejays” firstlogo=”https://static.sprtactn.co/teamlogos/ncaab/100/crei.png” secondfullname=”Tennessee Volunteers” secondlogo=”https://static.sprtactn.co/teamlogos/ncaab/100/ten.png” text=”Creighton vs Tennessee”][/teammatchup] | Tennessee -2.5 | |
|
Odds via bet365. Always shop for the best price using our NCAAB Odds page, which automatically surfaces the best lines for every game.
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No. 6 Clemson vs No. 2 Arizona Odds, Prediction
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Clemson vs Arizona Predictions:
Arizona -6 | Over/Under 151 | Final Score: Arizona 79, Clemson 73
[expertpickswidget league=”ncaab” gameid=”223950″ date=”20240328″ week=”” seasontype=””][/expertpickswidget]
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No. 5 San Diego State vs No. 1 UConn Odds, Prediction
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San Diego State vs UConn Predictions:
UConn -9 | Over/Under 135 | Final Score: UConn 72, San Diego State 63
[expertpickswidget league=”ncaab” gameid=”223956″ date=”20240328″ week=”” seasontype=””][/expertpickswidget]
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No. 4 Alabama vs No. 1 UNC Odds, Prediction
[gamematchup league=”ncaab” awaylogo=”https://static.sprtactn.co/teamlogos/ncaab/100/bama.png” awayname=”Alabama” awayslug=”alabama-crimson-tide” homelogo=”https://static.sprtactn.co/teamlogos/ncaab/100/nc.png” homename=”UNC” homeslug=”north-carolina-tar-heels” date=”Thursday, Mar 28″ time=”9:39pm ET” network=”CBS” col1text=”Spread” col2text=”Total” col3text=”Moneyline” col1awaytext=”+4″ col1awayline=”-110″ col1hometext=”-4″ col1homeline=”-110″ col2awaytext=”173.5″ col2hometext=”173.5″ col2awayline=”-110o / -110u” col2homeline=”-110o / -110u” col3awaytext=”+165″ col3hometext=”-200″ col3awayline=”” col3homeline=”” bookname=”bet365″ bookthumbnaillogo=”https://assets.actionnetwork.com/240081_Bet365ALT.png” bookreviewslug=”bet365″][/gamematchup]
Alabama vs UNC Predictions:
UNC -1 | Over/Under 158.5 | Final Score: UNC 80, Alabama 79
[expertpickswidget league=”ncaab” gameid=”223952″ date=”20240328″ week=”” seasontype=””][/expertpickswidget]
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No. 3 Illinois vs No. 2 Iowa State Odds, Prediction
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Illinois vs Iowa State Predictions:
Iowa State -1 | Over/Under 142 | Final Score: Iowa State 72, Illinois 71
[expertpickswidget league=”ncaab” gameid=”223907″ date=”20240328″ week=”” seasontype=””][/expertpickswidget]
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No. 11 NC State vs No. 2 Marquette Odds, Prediction
[gamematchup league=”ncaab” awaylogo=”https://static.sprtactn.co/teamlogos/ncaab/100/ncst.png” awayname=”NC State” awayslug=”north-carolina-state-wolfpack” homelogo=”https://static.sprtactn.co/teamlogos/ncaab/100/marq.png” homename=”Marquette” homeslug=”marquette-golden-eagles” date=”Friday, Mar 29″ time=”7:09pm ET” network=”CBS” col1text=”Spread” col2text=”Total” col3text=”Moneyline” col1awaytext=”+6.5″ col1awayline=”-110″ col1hometext=”-6.5″ col1homeline=”-110″ col2awaytext=”150.5″ col2hometext=”150.5″ col2awayline=”-110o / -110u” col2homeline=”-110o / -110u” col3awaytext=”+235″ col3hometext=”-290″ col3awayline=”” col3homeline=”” bookname=”bet365″ bookthumbnaillogo=”https://assets.actionnetwork.com/240081_Bet365ALT.png” bookreviewslug=”bet365″][/gamematchup]
NC State vs Marquette Predictions:
Marquette -8.5 | Over/Under 145.5 | Final Score: Marquette 77, NC State 69
[expertpickswidget league=”ncaab” gameid=”223940″ date=”20240329″ week=”” seasontype=””][/expertpickswidget]
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No. 5 Gonzaga vs No. 1 Purdue Odds, Prediction
[gamematchup league=”ncaab” awaylogo=”https://static.sprtactn.co/teamlogos/ncaab/100/gonz.png” awayname=”Gonzaga” awayslug=”gonzaga-bulldogs” homelogo=”https://static.sprtactn.co/teamlogos/ncaab/100/pur.png” homename=”Purdue” homeslug=”purdue-boilermakers” date=”Friday, Mar 29″ time=”7:39pm ET” network=”TBS/truTV” col1text=”Spread” col2text=”Total” col3text=”Moneyline” col1awaytext=”+4.5″ col1awayline=”-110″ col1hometext=”-4.5″ col1homeline=”-110″ col2awaytext=”154″ col2hometext=”154″ col2awayline=”-110o / -110u” col2homeline=”-110o / -110u” col3awaytext=”+165″ col3hometext=”-200″ col3awayline=”” col3homeline=”” bookname=”bet365″ bookthumbnaillogo=”https://assets.actionnetwork.com/240081_Bet365ALT.png” bookreviewslug=”bet365″][/gamematchup]
Gonzaga vs Purdue Predictions:
Purdue -4.5 | Over/Under 152.5 | Final Score: Purdue 79, Gonzaga 74
[expertpickswidget league=”ncaab” gameid=”223943″ date=”20240329″ week=”” seasontype=””][/expertpickswidget]
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No. 4 Duke vs No. 1 Houston Duke Odds, Prediction
[gamematchup league=”ncaab” awaylogo=”https://static.sprtactn.co/teamlogos/ncaab/100/dukd.png” awayname=”Duke” awayslug=”duke-blue-devils” homelogo=”https://static.sprtactn.co/teamlogos/ncaab/100/hou.png” homename=”Houston” homeslug=”houston-cougars” date=”Friday, Mar 29″ time=”9:39pm ET” network=”CBS” col1text=”Spread” col2text=”Total” col3text=”Moneyline” col1awaytext=”+3.5″ col1awayline=”-106″ col1hometext=”-3.5″ col1homeline=”-114″ col2awaytext=”133.5″ col2hometext=”133.5″ col2awayline=”-115o / -105u” col2homeline=”-115o / -105u” col3awaytext=”+140″ col3hometext=”-170″ col3awayline=”” col3homeline=”” bookname=”FanDuel” bookthumbnaillogo=”https://assets.actionnetwork.com/392973_FanDuel.png” bookreviewslug=”fanduel”][/gamematchup]
Houston vs Duke Predictions:
Houston -4 | Over/Under 134.5 | Final Score: Houston 70, Duke 65
[expertpickswidget league=”ncaab” gameid=”223955″ date=”20240329″ week=”” seasontype=””][/expertpickswidget]
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No. 3 Creighton vs No. 2 Tennessee Odds, Prediction
[gamematchup league=”ncaab” awaylogo=”https://static.sprtactn.co/teamlogos/ncaab/100/crei.png” awayname=”Creighton” awayslug=”creighton-bluejays” homelogo=”https://static.sprtactn.co/teamlogos/ncaab/100/ten.png” homename=”Tennessee” homeslug=”tennessee-volunteers” date=”Friday, Mar 29″ time=”10:09pm ET” network=”TBS/truTV” col1text=”Spread” col2text=”Total” col3text=”Moneyline” col1awaytext=”+2.5″ col1awayline=”-110″ col1hometext=”-2.5″ col1homeline=”-110″ col2awaytext=”144″ col2hometext=”144″ col2awayline=”-110o / -110u” col2homeline=”-110o / -110u” col3awaytext=”+125″ col3hometext=”-150″ col3awayline=”” col3homeline=”” bookname=”bet365″ bookthumbnaillogo=”https://assets.actionnetwork.com/240081_Bet365ALT.png” bookreviewslug=”bet365″][/gamematchup]
Creighton vs Tennesee Predictions:
Tennessee -4 | Over/Under 140.5 | Final Score: Tennessee 72, Creighton 68
[expertpickswidget league=”ncaab” gameid=”223920″ date=”20240329″ week=”” seasontype=””][/expertpickswidget]
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