ncaab-2-22-2025-picks-spreads-projections Cooper Flagg #2 of the Duke Blue Devils.

College Basketball Spreads, Projections, Expert Predictions for 2/22

We’re getting a jump on Saturday’s glorious college basketball slate. PRO Projections are out for the card. Needless to say, grade-A edges are piling up so fast that we may as well dive in early.

We’re covering six college hoops spread picks. As always, we’re basically taking our PRO line and stacking it up to the betting market to see where the advantages are.

Saturday’s premium selections are high-profile bangers: Illinois vs. Duke and Kentucky vs. Alabama, among others.

Let’s rack ’em up.


College Basketball Spreads, Projections, Expert Predictions for 2/22

Picks start at noon ET and run through the Duke-Illinois game at 8 p.m. All seven spreads are green-lighted from PRO Projections (B- grade or better) as solid plays. We’ll start with the biggest edge and work our way down the ratings.

The best pick for college basketball Saturday is a wrong-team-favored scenario.

At 6 p.m. the top selection is Boise State to cover vs. Nevada. Boise State is +1.5, but the PRO line is more like Boise State -4. It’s the first of two A+ picks.

PRO Projections Prediction: Boise State Against the Spread


Next up is Missouri (-1.5) at Arkansas. Projections make Missouri -5, the second of two A+ edges.

PRO Projections Prediction: Missouri Against the Spread


Miami’s been one of the most underwhelming teams in college hoops. We’re fading the Hurricanes again, with a play on Virginia Tech. VT is +3, but we make the Hokies favorites (-0.5), an A- edge.

PRO Projections Prediction: Virginia Tech Against the Spread


For Duke vs. Illinois, our data supports Illinois as an underdog. The Blue Devils are -10.5, but our fair spread comes out to just Duke -7. Illinois against the spread is an A- edge.

PRO Projections Prediction: Illinois Against the Spread


In the noon Eastern window, TCU is a solid look at Cincinnati. The Horned Frogs are catching eight points; our fair line is +5. The difference produces an A- edge by our ratings.

PRO Projections Prediction: TCU Against the Spread


Kentucky meets Alabama for a good one in Tuscaloosa. While the market line is Alabama -8.5, PRO Projections side with Kentucky, tabbing the Wildcats more like +6. It’s a B grade on Kentucky.

PRO Projections Prediction: Kentucky Against the Spread


PRO Projections Spread Picks for Saturday

  • Boise State
  • Missouri
  • Virginia Tech
  • Illinois
  • TCU
  • Kentucky

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