The Miami Marlins host the Tampa Bay Rays on May 16, 2025. First pitch from loanDepot park is scheduled for 7:10 p.m. EDT; the game will be broadcast on FDSSUN.
Find my MLB betting preview and Rays vs Marlins prediction below, as well as probable pitchers, betting trends, injury reports and more.
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- Rays vs Marlins picks: Marlins Moneyline
My Rays vs Marlins best bet is the Marlins moneyline. Make sure to find the best odds by checking our live MLB odds page.
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Rays vs Marlins Odds
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[playercomparison league=”mlb” date=”20250516″ title=”Rays vs Marlins Projected Starting Pitchers” awayplayerid=”165574″ awayplayerdisplay=”Taj Bradley (TB)” homeplayerid=”147483″ homeplayerdisplay=”Max Meyer (MIA)” stattype=”pitching”][/playercomparison]
William Boor’s Rays vs Marlins Preview, Betting Analysis
Teams returning from a road trip often underperform in the first game of their next series due to travel fatigue, body clock disruption and limited adjustment time.
When that next opponent is the Miami Marlins — a team not typically priced as elite — market perception may overvalue the returning team. That creates value in betting on the Marlins in Game 1 of a series.
Overall, this system has a 9% ROI since 2006. However, things get really enticing when we look at this season as the trend is 8-3 with an 18% ROI in 2025.
Pick: Rays Moneyline
Moneyline
For the reasons stated above, I’m backing the Rays moneyline.
Run Line (Spread)
I don’t see any value in betting the Rays vs. Marlins run line.
Over/Under
I’m going to pass on the Rays vs. Marlins over/under.
Rays vs Marlins Betting Trends
[bettingtrends title=”” gameid=”253793″ date=”20250516″][/bettingtrends]
[howtowatch gameid=”253793″ date=”20250516″][/howtowatch]
Rays vs Marlins starts at 7:10 p.m. EDT on Friday, live from loanDepot park. The game will be broadcast on FDSSUN.
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[gameforecast league=”mlb” gameid=”253793″ date=”20250516″][/gameforecast]
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