The Baltimore Orioles host the St. Louis Cardinals on May 27, 2025. First pitch from Oriole Park at Camden Yards is scheduled for 6:35 p.m. EDT; the game will be broadcast on FDSMW.
Read our Cardinals vs Orioles prediction and MLB player prop home run pick below.
[quickslipbasic bookname=”BetMGM” booklogo=”https://assets.actionnetwork.com/779359_BetMGM800x200@1x.png” image=”https://images.actionnetwork.com/blog/2025/05/Screenshot-2025-05-27-at-1.16.28-PM.png” buttontext=”Click To Bet Noot HR!” buttonlink=”https://switchboard.actionnetwork.com/v2/deeplink?deeplinkId[0]=ML1596579119&context=qs-articles”][/quickslipbasic]
[subheader sizedown=”false” text=”My Cardinals vs Orioles Prediction” center=”true” logo1url=”https://static.sprtactn.co/teamlogos/mlb/100/stl.png” link1=”https://www.actionnetwork.com/mlb/odds/st.-louis-cardinals” link1follow=”true” logo2url=”https://static.sprtactn.co/teamlogos/mlb/100/bal.png” link2=”https://www.actionnetwork.com/mlb/odds/baltimore-orioles” link2follow=”true”][/subheader]
- Cardinals vs Orioles Picks: Lars Nootbaar Home Run (+550, BetMGM)
My Cardinals vs Orioles best bet is on Lars Nootbaar to hit a home run. Make sure to find the best odds by checking our live MLB odds page.
_InlineAdBlock
Cardinals vs Orioles Odds, Spread
[gamematchup league=”mlb” awaylogo=”https://static.sprtactn.co/teamlogos/mlb/100/stl.png” awayname=”Cardinals” awayslug=”st.-louis-cardinals” homelogo=”https://static.sprtactn.co/teamlogos/mlb/100/bal.png” homename=”Orioles” homeslug=”baltimore-orioles” date=”Tuesday, May 27″ time=”6:35 p.m. ET” network=”FDSMW” col1text=”Spread” col2text=”Total” col3text=”Moneyline” col1awaytext=”-1.5″ col1awayline=”+145″ col1hometext=”+1.5″ col1homeline=”-175″ col2awaytext=”9″ col2hometext=”9″ col2awayline=”-110o / -110u” col2homeline=”-110o / -110u” col3awaytext=”-118″ col3hometext=”-102″ col3awayline=”” col3homeline=”” bookname=”BetMGM” bookthumbnaillogo=”https://assets.actionnetwork.com/902516_MGM2.png” bookreviewslug=”betmgm”][/gamematchup]
My Cardinals vs Orioles Betting Preview
St. Louis Cardinals Player Prop: Nootbaar Homer
Lars Nootbaar has been hitting well this season, and he’s in a good spot on Tuesday to go yard.
The ballpark is an upgrade for left-handed power hitters, and the weather shouldn’t be bad for hitting.
Orioles starting pitcher Tomoyuki Sugano has been crushed by lefties in his career, allowing a whopping 1.71 home runs per nine innings pitched to the side.
I make the fair odds on this home run prop under +500, making this a great bet.
Pick: Lars Nootbaar Home Run (+550, BetMGM)
[subheader sizedown=”true” text=”Cardinals vs Orioles Weather” center=”false”][/subheader]
[gameforecast league=”mlb” gameid=”255774″ date=”20250527″][/gameforecast]