MLB Predictions Friday, Best Bets, Prop Picks Today

With 15 games on the slate and all 30 teams in action, MLB bettors have no shortage of options to choose from when looking to place a wager.

Luckily, our systems and MLB betting experts have narrowed the options a bit as they’ve already dug through the latest MLB odds to make their predictions for tonight’s slate. So, continue reading as Friday’s MLB best bets are below.

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MLB Best Bets Today

The team logos in the table below represent each of the matchups that our MLB betting staff is targeting from today’s slate of games. Click on the team logos for any of the matchups below to navigate to a specific bet discussed in this article.

Game	Time (ET)	Pick
[teammatchup link=”#1″ firstfullname=”Milwaukee Brewers” firstlogo=”https://static.sprtactn.co/teamlogos/mlb/100/mil.png” secondfullname=”Cincinnati Reds” secondlogo=”https://images.actionnetwork.com/blog/2023/08/2023-mlb-logo-cincinnati-reds.png”][/teammatchup]	6:40 p.m.	Sean Paul’s Moneyline Pick
[teammatchup link=”#2″ firstfullname=”Philadelphia Phillies” firstlogo=”https://images.actionnetwork.com/blog/2023/08/2023-mlb-logo-philadelphia-phillies.png” secondfullname=”Washington Nationals” secondlogo=”https://images.actionnetwork.com/blog/2023/08/2023-mlb-logo-washington-nationals.png”][/teammatchup]	6:45 p.m.	Over/Under Prediction
[teammatchup link=”#3″ firstfullname=”Miami Marlins” firstlogo=”https://images.actionnetwork.com/blog/2023/08/2023-mlb-logo-miami-marlins.png” secondfullname=”Boston Red Sox” secondlogo=”https://images.actionnetwork.com/blog/2023/08/2023-mlb-logo-boston-red-sox.png”][/teammatchup]	7:10 p.m.	Kyle Murray’s Prop Pick
[teammatchup link=”#4″ firstfullname=”Seattle Mariners” firstlogo=”https://images.actionnetwork.com/blog/2023/08/2023-mlb-logo-seattle-mariners.png” secondfullname=”New York Mets” secondlogo=”https://images.actionnetwork.com/blog/2023/08/2023-mlb-logo-new-york-mets.png”][/teammatchup]	7:10 p.m.	PRO’s Top Projected Edge
[teammatchup link=”#5″ firstfullname=”New York Yankees” firstlogo=”https://static.sprtactn.co/teamlogos/mlb/100/nyyd.png” secondfullname=”St. Louis Cardinals” secondlogo=”https://images.actionnetwork.com/blog/2023/08/2023-mlb-logo-st-louis-cardinals.png”][/teammatchup]	8:15 p.m.	Bet Labs’ Featured Friday System
Specific betting recommendations come from the sportsbook offering preferred odds as of writing. Always shop for the best price using our MLB Odds page, which automatically surfaces the best lines for every game.

[anchor name=”1″][/anchor]

[subheader sizedown=”false” text=”Sean Paul’s Brewers vs Reds Best Bet: Back Cincinnati at Home”][/subheader]

[gameheader haspick=”true” picktext=”Reds Moneyline (+119)” league=”mlb” awaylogo=”https://static.sprtactn.co/teamlogos/mlb/100/mil.png” awayname=”Milwaukee Brewers” awayslug=”milwaukee-brewers” homelogo=”https://images.actionnetwork.com/blog/2023/08/2023-mlb-logo-cincinnati-reds.png” homename=”Cincinnati Reds” homeslug=”cincinnati-reds” date=”Friday, August 15″ time=”6:40 p.m. ET” network=”MLB.TV” bookname=”DraftKings ” bookprimarylogo=”https://assets.actionnetwork.com/477013_DraftKings@1x.png” bookreviewslug=”draftkings”][/gameheader]

By Sean Paul

The good thing, if you’re with me in backing the Reds here, is that they continue to win, even without Elly De La Cruz playing well. It’ll make a huge difference if that changes.

The Brewers have won 12 straight games, but all good things must come to an end. They won’t win every game for the rest of the year, and Nick Martinez has the right attack to limit an exciting Milwaukee offense.

I’ll take the plus money with the Reds at home.

Pick: Reds Moneyline (+119)

[teammatchup link=”#1″ shadow=”true” firstfullname=”Milwaukee Brewers” firstlogo=”https://static.sprtactn.co/teamlogos/mlb/100/mil.png” secondfullname=”Cincinnati Reds” secondlogo=”https://images.actionnetwork.com/blog/2023/08/2023-mlb-logo-cincinnati-reds.png”][/teammatchup]

[teammatchup link=”#2″ shadow=”true” firstfullname=”Philadelphia Phillies” firstlogo=”https://images.actionnetwork.com/blog/2023/08/2023-mlb-logo-philadelphia-phillies.png” secondfullname=”Washington Nationals” secondlogo=”https://images.actionnetwork.com/blog/2023/08/2023-mlb-logo-washington-nationals.png”][/teammatchup]

[teammatchup link=”#3″ shadow=”true” firstfullname=”Miami Marlins” firstlogo=”https://images.actionnetwork.com/blog/2023/08/2023-mlb-logo-miami-marlins.png” secondfullname=”Boston Red Sox” secondlogo=”https://images.actionnetwork.com/blog/2023/08/2023-mlb-logo-boston-red-sox.png”][/teammatchup]

[teammatchup link=”#4″ shadow=”true” firstfullname=”Seattle Mariners” firstlogo=”https://images.actionnetwork.com/blog/2023/08/2023-mlb-logo-seattle-mariners.png” secondfullname=”New York Mets” secondlogo=”https://images.actionnetwork.com/blog/2023/08/2023-mlb-logo-new-york-mets.png”][/teammatchup]

[teammatchup link=”#5″ shadow=”true” firstfullname=”New York Yankees” firstlogo=”https://static.sprtactn.co/teamlogos/mlb/100/nyyd.png” secondfullname=”St. Louis Cardinals” secondlogo=”https://images.actionnetwork.com/blog/2023/08/2023-mlb-logo-st-louis-cardinals.png”][/teammatchup]

[anchor name=”2″][/anchor]

[subheader sizedown=”false” text=”Action Network’s Phillies vs Nationals Best Bet: Bet the Under”][/subheader]

[gameheader haspick=”true” picktext=”Under 8 (-110)” league=”mlb” awaylogo=”https://images.actionnetwork.com/blog/2023/08/2023-mlb-logo-philadelphia-phillies.png” awayname=”Philadelphia Phillies” awayslug=”philadelphia-phillies” homelogo=”https://images.actionnetwork.com/blog/2023/08/2023-mlb-logo-washington-nationals.png” homename=”Washington Nationals” homeslug=”washington-nationals” date=”Friday, August 15″ time=”6:45 p.m. ET” network=”MLB.TV” bookname=”Fanatics Sportsbook” bookprimarylogo=”https://assets.actionnetwork.com/542724_Fanatics-banner-logo.png” bookreviewslug=”fanatics-sportsbook”][/gameheader]

By Action Network Staff

Today’s total is set at 8, which fits perfectly with Evan Abrams’ “Steam Unders with Low O/U Support” system. This strategy targets regular-season games in the 8-10 run range where sharp money has pushed the total down from the opener, but public betting still leans toward the over.

Pick: Under 8 (-110)

[quickslipbasic bookname=”Fanatics” booklogo=”https://assets.actionnetwork.com/573837_FanaticsSportsbook20ALT.png” image=”https://images.actionnetwork.com/blog/2025/08/Screenshot-2025-08-15-at-6.47.45%E2%80%AFAM.png” buttontext=”Parlay These Picks Instantly!” buttonlink=”https://www.scoresandodds.com/all/parlay?quickslip=1&onelink=/5kut/1c9piva6?sharedBy=QS_0105&ref=10001″][/quickslipbasic]

[anchor name=”3″][/anchor]

[subheader sizedown=”false” text=”Kyle Murray’s Marlins vs Red Sox Best Bet: Fade Alcantara”][/subheader]

[gameheader haspick=”true” picktext=”Sandy Alcantara Under 4.5 Strikeouts (-125)” league=”mlb” awaylogo=”https://images.actionnetwork.com/blog/2023/08/2023-mlb-logo-miami-marlins.png” awayname=”Miami Marlins” awayslug=”miami-marlins” homelogo=”https://images.actionnetwork.com/blog/2023/08/2023-mlb-logo-boston-red-sox.png” homename=”Boston Red Sox” homeslug=”boston-red-sox” date=”Friday, August 15″ time=”7:10 p.m. ET” network=”MLB.TV” bookname=”DraftKings ” bookprimarylogo=”https://assets.actionnetwork.com/477013_DraftKings@1x.png” bookreviewslug=”draftkings”][/gameheader]

By Kyle Murray

The Red Sox team have a totally different look than they did a month ago, as Alex Bregman and Masataka Yoshida bring two low-strikeout guys into the heart of the lineup. As a result, Boston’s projected lineup has a 21.1% strikeout against right-handed pitching this season.

Meanwhile, Sandy Alcantara hasn’t been quite the same pitcher that he was before his Tommy John surgery and is now giving up more power and missing fewer bats. He has just a 16.8% strikeout rate and a 24.5% CSW% on the season.

Pick: Sandy Alcantara Under 4.5 Strikeouts (-125)

[expertpickswidget league=”mlb” gameid=”259114″ date=”20250815″ week=”” seasontype=””][/expertpickswidget]

[anchor name=”4″][/anchor]

[subheader sizedown=”false” text=”PRO’s Mariners vs Mets Best Bet: Value in Castillo’s Under”][/subheader]

[gameheader haspick=”true” picktext=”Luis Castillo Under 4.5 Strikeouts (+125)” league=”mlb” awaylogo=”https://images.actionnetwork.com/blog/2023/08/2023-mlb-logo-seattle-mariners.png” awayname=”Seattle Mariners” awayslug=”seattle-mariners” homelogo=”https://images.actionnetwork.com/blog/2023/08/2023-mlb-logo-new-york-mets.png” homename=”New York Mets” homeslug=”new-york-mets” date=”Friday, August 15″ time=”7:10 p.m. ET” network=”MLB.TV” bookname=”FanDuel” bookprimarylogo=”https://assets.actionnetwork.com/122955_FanDuelSportsBook@1x.jpg” bookreviewslug=”fanduel”][/gameheader]

By Action PRO

PRO projects Mariners’ starter Luis Castillo to notch 4.37 strikeouts tonight, which represents an 11.3% edge against the market.

Pick: Luis Castillo Under 4.5 Strikeouts (+125)

[relatedarticle articleimageurl=”https://images.actionnetwork.com/blog/2025/08/jazzchisholm-1-1.jpg” linktext=”MLB Picks Friday: Smart Predictions for Yankees vs Cardinals” link=”https://www.actionnetwork.com/mlb/mlb-picks-friday-predictions-yankees-vs-cardinals-august-15″][/relatedarticle]

[anchor name=”5″][/anchor]

[subheader sizedown=”false” text=”Bet Labs’ Yankees vs Cardinals Best Bet: System Backs Yankees on Road”][/subheader]

[gameheader haspick=”true” picktext=”Yankees Moneyline (-130)” league=”mlb” awaylogo=”https://static.sprtactn.co/teamlogos/mlb/100/nyyd.png” awayname=”New York Yankees” awayslug=”new-york-yankees” homelogo=”https://images.actionnetwork.com/blog/2023/08/2023-mlb-logo-st-louis-cardinals.png” homename=”St. Louis Cardinals” homeslug=”st.-louis-cardinals” date=”Friday, August 15″ time=”8:15 p.m. ET” network=”MLB.TV” bookname=”BetMGM” bookprimarylogo=”https://assets.actionnetwork.com/779359_BetMGM800x200@1x.png” bookreviewslug=”betmgm”][/gameheader]

By Bet Labs

The “Road Tilt in the Dead Heat” system targets MLB regular-season games in which two evenly matched teams — based on win percentages — meet in a non-division setting, and one is quietly priced as a modest road favorite. When there’s no clear performance gap, but the market still tilts slightly toward the road team, it suggests underlying confidence from oddsmakers that may not be reflected in public perception. This model seizes those subtle cues and leans into narrow value created by the near-identical records and overlooked road strength.

Overall, this system is 289-181 (61%) and has generated a 10% ROI. This season, the system is running hot as it has cashed 65% of its picks (22-12) and generated a 15% ROI.

[betlabsembed systemid=”1479163″ systemname=”Evan Abrams / Bet Labs – Road Tilt in the Dead Heat” leaguename=”mlb” filters=”%7B%22list%22%3A%5B%22the%20team%20is%20the%20Visitor%20team%22%2C%22the%20team’s%20win%20percent%20differential%20is%20between%20-3%20and%203%22%2C%22the%20closing%20moneyline%20is%20between%20-136%20and%20-121%22%2C%22the%20game%20is%20a%20Non-Division%20game%22%2C%22the%20game%20is%20played%20during%20the%20Regular%20season%22%5D%7D” amountwon=”$4,580″ record=”289-181-0″ winpct=”61%”][/betlabsembed]

Pick: Yankees Moneyline (-130)

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MLB Predictions Friday, Best Bets, Prop Picks Today — August 15