We’re taking advantage of Tuesday’s full MLB slate with a bunch of different betting predictions from PRO.
This article delves into the best moneyline picks, home run bets, and strikeout props from our expert database today. Backed by the accuracy of PRO Projections and additional insights from PRO Report, plenty of action awaits.
In total, we provide six carefully considered picks, with two from each category, ensuring comprehensive coverage of the betting landscape.
Below, you’ll find a plus-money ‘dog sharps like, a home-run hitter at +750 who is due, and more!
The first game is slated for 6:40 p.m. ET, so let’s dive into the selections.
MLB Odds, Picks for 4/22
Moneyline Predictions
Starting with moneyline picks, we have a noteworthy matchup between the Cardinals and the Braves. With the Braves favored at -144 and the Cardinals at +121, the hot bet for sharp bettors and top experts is backing the Cardinals.
According to PRO’s line predictor, there’s a strong probability of the line dropping to Braves -140, demonstrating a valuable edge in this scenario on the underdogs.
PRO Pick: Cardinals Moneyline
Meanwhile, in Rangers vs. Athletics, the odds show the A’s at -130 and the Rangers at +110. Sharps and substantial money are flooding the Athletics, evidently fading veteran Texas pitcher Patrick Corbin. Here, PRO Report gives a clear, one-sided indication of where smart money is moving – on the home team.
PRO Pick: A’s Moneyline
Home Run Predictions
In terms of home run picks, Anthony Santander of the Blue Jays offers an attractive option at +375 against the Astros. The park conditions favor right-handed hitters, and our projections indicate a strong +4.1% edge, anticipating 0.29 home runs for him.
PRO Pick: Anthony Santander Home Run (+375)
Additionally, keep an eye on Connor Norby of the Marlins at +750. Despite not having hit a home run this year, Norby shows promise, with PRO Projections foreseeing an eventual breakout performance, providing a +4.7% edge.
PRO Pick: Connor Norby Home Run (+750)
Strikeout Props
Lastly, our strikeout props include Griffin Canning of the Mets, with FanDuel offering a line of over 4.5 strikeouts at -106 vs. the Phillies. Our projections predict Canning achieving 5.4 strikeouts against Philly, creating a huge edge on the over.
PRO Pick: Griffin Canning Over 4.5 Strikeouts
Also, consider the ‘over’ with Jack Flaherty pitching for the Tigers against the Padres. With an over/under set at 5.5 strikeouts, Flaherty is projected to surpass this with 6.2 strikeouts, per PRO.
PRO Pick: Jack Flaherty Over 5.5 Strikeouts
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Our PRO signals flag far more great picks than our staff could author each day — that’s where Action AI comes in. Using generative AI, signals that hit a high grade threshold are written up into articles that are then vetted and edited by a human to help us get you all the sharp action. Read more about how it works here.