mlb-moneyline-over-under-picks-4-4-2025

MLB Moneyline, Over/Under Picks: Pirates vs Yankees, Athletics vs Rockies

It’s an action-packed slate MLB Friday, and PRO’s serving up both sharp moneyline and over/under picks in the afternoon.

With 14 games on the card today, our focus sharpens on two particular matchups buzzing with potential betting value: the Yankees vs. Pirates and the Athletics vs. Rockies.

PRO Report meticulously compiles insights from betting resources, including proprietary trends, expert projections, and big bet trackers, to help you make the most informed wagers.

Yankees vs. Pirates features sharps, projections and experts agreeing on the same pick.

The top Athletics vs. Rockies prediction, meanwhile, hinges on the weather!


Best MLB Moneyline, Over/Under Picks for 4/4

Pirates vs. Yankees Pick Friday

Let’s start with the Yankees vs. Pirates clash. The Pirates will start pitcher Mitch Keller, who faces off against the Yankees’ Max Fried.

PRO Report shows a convergence of sharp bettors, expert projections, and top experts favoring the Pirates on the moneyline. Historically, when such a consensus forms, there’s often value to be found. The Yankees are currently favored at -165, while the Pirates sit at +140. However, our in-house PRO Projections suggest a fair moneyline for the Pirates at +116, indicating potential value to upset the Yankees at home.

PRO Pick: Pirates Moneyline

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Athletics vs. Rockies Pick Friday

In the Athletics vs. Rockies matchup, we’re targeting the total, specifically betting on the game to go under 9.5 runs. This isn’t just a hunch—it’s supported by our “Wind Blowing In” system, which has historically profited when similar weather conditions are present, especially at Coors Field.

Sharp bettors are also aligning with the under, adding weight to this pick. The opening game of this series provides a fresh slate for both teams, but the environmental factors coupled with the historical data make this under bet the ideal route.

PRO Pick: Athletics vs. Rockies Under

[quickslipbasic bookname=”BetMGM” booklogo=”https://assets.actionnetwork.com/779359_BetMGM800x200@1x.png” image=”https://images.actionnetwork.com/blog/2025/04/IMG_1917.jpeg” buttontext=”Instantly Bet the Under!” buttonlink=”https://switchboard.actionnetwork.com/v2/deeplink?deeplinkId[0]=ML1435846851&context=qs-articles”][/quickslipbasic]


Our PRO signals flag far more great picks than our staff could author each day — that’s where Action AI comes in. Using generative AI, signals that hit a high grade threshold are written up into articles that are then vetted and edited by a human to help us get you all the sharp action. Read more about how it works here.

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