For Friday, June 6, I’m on four MLB home run props: Vladimir Guerrero Jr. (against the Twins), Brent Rooker and Jacob Wilson (against the Orioles), and Ronald Acuna Jr. (against the Giants).
Continue below for my MLB home run prop bets and HR parlay for Friday.
[quickslipbasic bookname=”BetMGM” booklogo=”https://assets.actionnetwork.com/779359_BetMGM800x200@1x.png” image=”https://images.actionnetwork.com/blog/2025/06/Screenshot-2025-06-06-at-9.05.16%E2%80%AFAM.png” buttontext=”+10498 Home Run Parlay on BetMGM” buttonlink=”https://sharpside.com/books/betmgm/passthrough?deeplinkId[0]=ML1613873057&deeplinkId[1]=ML1613884459&deeplinkId[2]=ML1613837380&context=qs-articles”][/quickslipbasic]
MLB Home Run Props, Picks, Odds — Friday, June 6
| Time (ET) | Player Prop |
|---|---|
| 8:10 p.m. | [teammatchup shadow=”false” link=”#2″ firstfullname=”Toronto Blue Jays” firstlogo=”https://static.sprtactn.co/teamlogos/mlb/100/tor.png” text=”Vladimir Guerrero Jr. Home Run (+550)”][/teammatchup] |
| 10:05 p.m. | [teammatchup shadow=”false” link=”#2″ firstfullname=”Athletics” firstlogo=”https://static.sprtactn.co/teamlogos/mlb/100/oak.png” text=”Brent Rooker Home Run (+475)”][/teammatchup] |
| 10:05 p.m. | [teammatchup shadow=”false” link=”#2″ firstfullname=”Athletics” firstlogo=”https://static.sprtactn.co/teamlogos/mlb/100/oak.png” text=”Jacob Wilson Home Run (+850)”][/teammatchup] |
| 10:15 p.m. | [teammatchup shadow=”false” link=”#2″ firstfullname=”Atlanta Braves” firstlogo=”https://static.sprtactn.co/teamlogos/mlb/100/atl.png” text=”Ronald Acuna Jr. Home Run (+475)”][/teammatchup] |
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Specific betting recommendations come from the sportsbook offering preferred odds as of writing. Always shop for the best price using our MLB Odds page, which automatically surfaces the best lines for every game.
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MLB Home Run Picks for June 6
[subheader sizedown=”true” text=”Vladimir Guerrero Jr. (+550)” subtext=”at Twins (SP: RHP Bailey Ober)” center=”false” logo1url=”https://static.sprtactn.co/teamlogos/mlb/100/tor.png” link1=”” link1follow=”true” logo2url=”” link2=”” link2follow=”true” trailinglogourl=”https://assets.actionnetwork.com/859377_Bet365@1x.png” trailinglink=”” trailinglinkfollow=”true”][/subheader]
Vladimir Guerrero Jr. isn’t showing the same home-run hitting prowess as the past, but the underlying numbers have been good this season and the matchup is a good one.
Twins starter Bailey Ober has been a big plus matchup in his career for righty power, with a 1.56 HR/9 to go along with a massive 48.1% fly-ball rate and high hard contact.
I have the true odds on Guerrero 100 points lower today, making this a great EV bet.
[subheader sizedown=”true” text=”Brent Rooker (+475)” subtext=”vs Orioles (SP: RHP Dean Kremer)” center=”false” logo1url=”https://static.sprtactn.co/teamlogos/mlb/100/oak.png” link1=”” link1follow=”true” logo2url=”” link2=”” link2follow=”true” trailinglogourl=”https://assets.actionnetwork.com/859377_Bet365@1x.png” trailinglink=”” trailinglinkfollow=”true”][/subheader]
I’m going heavy on A’s hitters tonight.
Orioles starter Dean Kremer has been a plus matchup for power to both sides of the plate, with a career 40% fly-ball rate.
Sutter Health Park is one of the best in the majors for HRs, and the weather should be near perfect, with temps in the high-80s and wind blowing out at 10 mph.
I have the true odds here around +300, making this a good bet.
[subheader sizedown=”true” text=”Jacob Wilson (+850)” subtext=”vs Orioles (SP: RHP Dean Kremer)” center=”false” logo1url=”https://static.sprtactn.co/teamlogos/mlb/100/oak.png” link1=”” link1follow=”true” logo2url=”” link2=”” link2follow=”true” trailinglogourl=”https://assets.actionnetwork.com/477013_DraftKings@1x.png” trailinglink=”” trailinglinkfollow=”true”][/subheader]
Jacob Wilson isn’t a huge power guy, but that isn’t stopping him from hitting bombs this season — he has eight so far.
I have the true odds here more than 100 points lower, making this a great bet.
[subheader sizedown=”true” text=”Ronald Acuna Jr. (+475)” subtext=”at Giants (SP: RHP Hayden Birdsong)” center=”false” logo1url=”https://static.sprtactn.co/teamlogos/mlb/100/atl.png” link1=”” link1follow=”true” logo2url=”” link2=”” link2follow=”true” trailinglogourl=”https://assets.actionnetwork.com/779359_BetMGM800x200@1x.png” trailinglink=”” trailinglinkfollow=”true”][/subheader]
I hate this ballpark for Ronald Acuna Jr., but the matchup and odds are too good to pass up.
Giants starter Hayden Birdsong has been a big plus matchup for righty power in his career, allowing 1.60 HR/9 despite playing in the most pitcher-friendly ballpark in the league.
Acuna is one of the best power hitters in the league, and these odds are just far too high.
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