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MLB Best Bets, Prop Picks, Saturday Predictions

Thanks to a doubleheader, the Major League Baseball schedule for Saturday, May 24, features 16 games. Our experts are all over it with four MLB Best Bets.

Among their MLB picks and predictions for Saturday are two player props and two first five innings (F5) moneyline bets for Royals vs Twins, Blue Jays vs Rays, Guardians vs Tigers and Dodgers vs Mets.

Find our MLB Best Bets and a parlay of our picks below.

[quickslipbasic bookname=”BetMGM” booklogo=”https://assets.actionnetwork.com/779359_BetMGM800x200@1x.png” image=”https://images.actionnetwork.com/blog/2025/05/Screenshot-2025-05-24-at-7.55.22%E2%80%AFAM.png” buttontext=”+2132 MLB Best Best Parlay” buttonlink=”https://sharpside.com/books/betmgm/passthrough?deeplinkId[0]=ML1588210950&deeplinkId[1]=ML1589402596&deeplinkId[2]=ML1588288247&context=qs-articles”][/quickslipbasic]


MLB Best Bets, Props, Picks, Predictions — 5/24

The team logos in the table below represent each of the matchups that our betting staff is targeting from the Saturday MLB games. Click on the team logos for any of the matchups below to navigate to a specific MLB prediction.

Game Time (ET) Pick
[teammatchup link=”#2″ firstfullname=”Toronto Blue Jays” firstlogo=”https://static.sprtactn.co/teamlogos/mlb/100/tor.png” secondfullname=”Tampa Bay Rays” secondlogo=”https://images.actionnetwork.com/blog/2023/08/2023-mlb-logo-tampa-bay-rays.png”][/teammatchup] 7:05 p.m.
[teammatchup link=”#3″ firstfullname=”Cleveland Guardians” firstlogo=”https://images.actionnetwork.com/blog/2023/08/2023-mlb-logo-cleveland-guardians.png” secondfullname=”Detroit Tigers” secondlogo=”https://assets.actionnetwork.com/461059_det_n.png”][/teammatchup] 7:15 p.m.
[teammatchup link=”#4″ firstfullname=”Los Angeles Dodgers” firstlogo=”https://images.actionnetwork.com/blog/2023/08/2023-mlb-logo-los-angeles-dodgers.png” secondfullname=”New York Mets” secondlogo=”https://images.actionnetwork.com/blog/2023/08/2023-mlb-logo-new-york-mets.png”][/teammatchup] 7:15 p.m.
[teammatchup link=”#1″ firstfullname=”Kansas City Royals” firstlogo=”https://images.actionnetwork.com/blog/2023/08/2023-mlb-logo-kansas-city-royals.png” secondfullname=”Minnesota Twins” secondlogo=”https://static.sprtactn.co/teamlogos/mlb/100/mind.png”][/teammatchup] 2:10 p.m.
Specific betting recommendations come from the sportsbook offering preferred odds as of writing. Always shop for the best price using our MLB Odds page, which automatically surfaces the best lines for every game.

[relatedarticle articleimageurl=”https://images.actionnetwork.com/blog/2025/05/Ohtani-LAD-5242025.jpg” linktext=”Dodgers vs Mets Prediction, Pick, Odds for Saturday, May 24″ link=”https://www.actionnetwork.com/mlb/los-angeles-dodgers-vs-new-york-mets-prediction-pick-odds-saturday-may-24-qs”][/relatedarticle]


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[subheader sizedown=”false” text=”Dylan Wilkerson’s Royals vs Twins F5 Prediction”][/subheader]

[gameheader haspick=”true” picktext=”Royals First Five Innings Moneyline (+100)” league=”mlb” awaylogo=”https://images.actionnetwork.com/blog/2023/08/2023-mlb-logo-kansas-city-royals.png” awayname=”Kansas City Royals” awayslug=”kansas-city-royals” homelogo=”https://static.sprtactn.co/teamlogos/mlb/100/mind.png” homename=”Minnesota Twins” homeslug=”minnesota-twins” date=”Saturday, May 24″ time=”2:10 p.m. ET” network=”MLB.TV” bookname=”bet365″ bookprimarylogo=”https://assets.actionnetwork.com/859377_Bet365@1x.png” bookreviewslug=”bet365″][/gameheader]

By Dylan Wilkerson

The Royals are sending out veteran Michael Wacha to the mound to face the Twins.

Wacha has had success against this Twins lineup, allowing only a .219 xBA and tallying a whiff rate of over 20%. Wacha has also done a great job of avoiding hard-hit balls, as he is in the 83rd percentile for average exit velocity allowed.

The Royals offense gets the opportunity to tee off on Twins pitcher Zebby Matthews, whom the Royals have had success against in the past.

Kansas City’s xBA against Matthews is a whopping .348, and the average exit velocity allowed (90 mph) has to be concerning for Twins fans.

Although it is a small sample size, I expect the Royals to jump on Matthews early.

Pick: Royals First Five Innings Moneyline (+100)



[anchor name=”2″][/anchor]

[subheader sizedown=”false” text=”Dylan Wilkerson’s Blue Jays vs Rays Home Run Prop”][/subheader]

[gameheader haspick=”true” picktext=”Jonathan Aranda Over 0.5 Home Runs (+480)” league=”mlb” awaylogo=”https://static.sprtactn.co/teamlogos/mlb/100/tor.png” awayname=”Toronto Blue Jays” awayslug=”toronto-blue-jays” homelogo=”https://images.actionnetwork.com/blog/2023/08/2023-mlb-logo-tampa-bay-rays.png” homename=”Tampa Bay Rays” homeslug=”tampa-bay-rays” date=”Saturday, May 24″ time=”7:05 p.m. ET” network=”MLB.TV” bookname=”FanDuel” bookprimarylogo=”https://assets.actionnetwork.com/122955_FanDuelSportsBook@1x.jpg” bookreviewslug=”fanduel”][/gameheader]

By Dylan Wilkerson

This matchup is too much to ignore.

Jonathan Aranda shown great improvements this season, and he has had success against Jose Berrios in his career. Berrios is having a rough year and is currently allowing his third-highest average exit velocity in his 10 seasons in MLB.

Aranda’s xBA against Berrios is .405, and he has an xSLG of 1.216. He has totaled three home runs against Berrios in only 11 plate appearances.

Aranda hasn’t homered since May 13, so why not get back on track for the holiday weekend?

Pick: Jonathan Aranda Over 0.5 Home Runs (+480)



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[subheader sizedown=”false” text=”Charlie Wright’s Guardians vs Tigers Pitcher Prop Pick”][/subheader]

[gameheader haspick=”true” picktext=”Luis L. Ortiz Over 4.5 Strikeouts (-132)” league=”mlb” awaylogo=”https://images.actionnetwork.com/blog/2023/08/2023-mlb-logo-cleveland-guardians.png” awayname=”Cleveland Guardians” awayslug=”cleveland-guardians” homelogo=”https://assets.actionnetwork.com/461059_det_n.png” homename=”Detroit Tigers” homeslug=”detroit-tigers” date=”Saturday, May 24″ time=”7:15 p.m. ET” network=”FOX” bookname=”FanDuel” bookprimarylogo=”https://assets.actionnetwork.com/122955_FanDuelSportsBook@1x.jpg” bookreviewslug=”fanduel”][/gameheader]

By Charlie Wright

The Guardians have developed Ortiz into a legitimate strikeout pitcher this season. They’ve made a few arsenal tweaks and a pitch profile adjustment — the changes have given Ortiz quality options for both righties and lefties.

Ortiz has a career-high 26.5% K%. His 12.8% SwStr% and 29.0% CSW% are his highest since his brief four-start debut in 2022. It’s a huge improvement from his 8.8% SwStr% and 24.9% CSW% last season.

Ortiz’s fastball performed well in 2024, but he didn’t have much else. Since coming to Cleveland, he’s added more drop to his slider while maintaining the velocity. The pitch has a massive 42.5% whiff rate.

The right-hander has also reintroduced a changeup (that he barely threw last season). After using the pitch just 0.9% of the time in 2024, it’s up at 13.3% this year. Ortiz’s changeup has never had a Stuff+ above 84, but it’s a solid 97 now. The slider and changeup give him swing-and-miss options to both righties and lefties.

The Tigers have been productive on offense, but they have plenty of players in their lineup who are strikeout prone. Detroit has the 10th-highest K% vs. RHP over the past 30 days; it is eighth on the season.

Detroit will throw several lefties at Ortiz, which isn’t a problem anymore. He has nearly identical strikeout rates to both sides of the plate (26.7% vs. righties; 26.4% vs. lefties) this season.

Getting knocked around is the concern as Ortiz has allowed a ton of hard contact this season. His xFIP and SIERA are both below 4.00, so maybe his 4.66 ERA will improve.

If he can hang in there for around five innings, he has a good shot at racking up at least five strikeouts.

Pick: Luis L. Ortiz Over 4.5 Strikeouts (-132)

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[anchor name=”4″][/anchor]

[subheader sizedown=”false” text=”Dylan Wilkerson’s Dodgers vs Mets F5 Prediction”][/subheader]

[gameheader haspick=”true” picktext=”Dodgers First Five Innings Moneyline (-105)” league=”mlb” awaylogo=”https://images.actionnetwork.com/blog/2023/08/2023-mlb-logo-los-angeles-dodgers.png” awayname=”Los Angeles Dodgers” awayslug=”los-angeles-dodgers” homelogo=”https://images.actionnetwork.com/blog/2023/08/2023-mlb-logo-new-york-mets.png” homename=”New York Mets” homeslug=”new-york-mets” date=”Saturday, May 24″ time=”7:15 p.m. ET” network=”FOX” bookname=”BetMGM” bookprimarylogo=”https://assets.actionnetwork.com/779359_BetMGM800x200@1x.png” bookreviewslug=”betmgm”][/gameheader]

By Dylan Wilkerson

The Dodgers have a great track record against Mets left-hander David Peterson.

Peterson has faced a batter in a Dodgers uniform nearly 100 times. He has given up hits in 37 of those plate appearances, and 14 of these hits came from the top of the lineup in Shohei Ohtani, Mookie Betts and Freddie Freeman.

Peterson’s xBA against the Dodgers is .343, and his other stats aren’t much better against this team. The average launch angle allowed is nearly 11 degrees, and his average exit velocity allowed is just shy of 93 mph.

On the other hand, Dodgers right-hander Tony Gonsolin has done a great job generating whiffs against this Mets lineup. He has limited the long ball, avoided hard hits and has a season-long xBA of .222.

I expect the Dodgers get out on top early in this one.

Pick: Dodgers First Five Innings Moneyline (-105)