The Seattle Mariners host the Milwaukee Brewers on July 22, 2025. First pitch from T-Mobile Park is scheduled for 9:40 p.m. EDT; the game will be broadcast on MLB Network.
Read our Brewers vs Mariners prediction and MLB same-game parlay picks below.
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[subheader sizedown=”false” text=”My Brewers vs Mariners Prediction” center=”true” logo1url=”https://static.sprtactn.co/teamlogos/mlb/100/mil.png” link1=”https://www.actionnetwork.com/mlb/odds/milwaukee-brewers” link1follow=”true” logo2url=”https://static.sprtactn.co/teamlogos/mlb/100/sea.png” link2=”https://www.actionnetwork.com/mlb/odds/seattle-mariners” link2follow=”true”][/subheader]
- Brewers ML
- Jacob Misiorowski 10+ Strikeouts
Parlay Odds: +1500 (DraftKings)
Brewers vs Mariners Odds, Spread, Best Bet
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Brewers vs Mariners Run Line: Brewers +1.5 (-210); Mariners -1.5 (+170)
Brewers vs Mariners Total: 6.5 (O -125 / U +105)
Brewers vs Mariners Moneyline: Brewers +105; Mariners -125
Brewers vs Mariners Best Bet: Brewers ML & Jacob Misiorowski 10+ Strikeouts
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Brewers vs Mariners Preview, Parlay
I’m betting on the Brewers to win in a long-shot play focused on Jacob Misiorowski.
Miz has been phenomenal since joining the big leagues, posting a 4-1 record with a 2.83 ERA with 33 strikeouts across five starts. He struck out 12 Dodgers in his last start, looking untouchable.
While throwing double-digit strikeouts again is a tall task, Misiorowski has the tools to obtain all 10. He’s only going to throw longer into games as his rookie season progresses, and I think the Brewers want to expose him to more high-pressure situations ahead of the playoff push.
I’m betting that the Brew Crew earn a road victory behind their new young ace.
Brewers vs Mariners Parlay
- Brewers ML
- Jacob Misiorowski 10+ Strikeouts
Parlay Odds: +1500 (DraftKings)
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Brewers vs Mariners Betting Trends
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[howtowatch gameid=”258062″ date=”20250722″][/howtowatch]