The Miami Marlins (15-26) take on the Chicago Cubs (25-18) on Wednesday, May 14, 2025. First pitch from Wrigley Field is scheduled for 7:40 p.m. ET; the game will be broadcast on Marquee and FanDuel Sports Florida.
The Cubs enter as -220 moneyline favorites with the over/under set at 7.5.
Find Marlins vs Cubs predictions for Wednesday below, as well as probable pitchers, betting trends and more.
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- Marlins vs Cubs Pick: Under 7.5
My Cubs vs. Marlins best bet is on both teams to stay under the total. Make sure to find the best odds by checking our live MLB odds page.
Miami Marlins vs Chicago Cubs Odds
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Marlins vs Cubs Projected Starting Pitchers
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Marlins vs Cubs Preview, Prediction
By Bet Labs
Wednesday’s Marlins vs. Cubs series finale fits a historically profitable PRO System that boasts a 15.5% ROI lifetime.
The main thesis of the system is betting unders at Wrigley Field — a stadium in which weather can significantly impact scoring — when the wind is blowing in.
When the wind blows in or across and the total opens between 8–13, unders become highly valuable.
Wrigley is uniquely sensitive to weather due to field orientation and the fact that it doesn’t have a dome, making it the premier ballpark for wind-based betting edges.
Marlins vs Cubs Prediction, Over/Under Pick
In addition to the Wrigley under trend, this game features a pitching matchup between Miami’s Ryan Weathers and Chicago’s Jameson Taillon.
Weathers is making his return to the Marlins’ staff after a rehab assignment in the minors. Taillon, meanwhile, has a much bigger sample size on the season.
Taillon has given up three or fewer earned runs in six of his eight starts this season. While he gave up five earned runs his last time out, that came against a Mets team that’s one of the best scoring groups in MLB.
Simply put, the Marlins are not that.
Miami ranks 16th in MLB in runs per game at 4.15, per TeamRankings. Over its last three games, that number has dropped to 2.67 — the fifth-worst mark in baseball over that span.
Trust the under at Wrigley once again.
Pick: Under 7.5
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Moneyline
We don’t have a pick on the moneyline in this series finale between the Marlins and Cubs.
Run Line (Spread)
Like the moneyline, we’re staying away from the run line here.
Over/Under
Our best bet for this game is for both teams to go under the total. Wrigley Field is infamous for allowing wind to impact scoring, and with the wind blowing in today, we’re betting the under.
Marlins vs Cubs Betting Trends
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