The Minnesota Twins host the Cleveland Guardians on May 19, 2025. First pitch from Target Field is scheduled for 7:40 p.m. EDT; the game will be broadcast on CLEG.
Find my MLB betting preview and Guardians vs Twins prediction below, as well as probable pitchers, betting trends, injury reports and more.
[quickslipbasic bookname=”BetMGM” booklogo=”https://assets.actionnetwork.com/779359_BetMGM800x200@1x.png” image=”https://images.actionnetwork.com/blog/2025/05/Screenshot-2025-05-19-at-8.21.51%E2%80%AFAM.png” buttontext=”Tail This Pick Instantly!” buttonlink=”https://switchboard.actionnetwork.com/v2/deeplink?deeplinkId[0]=ML1575983885&context=qs-articles”][/quickslipbasic]
[subheader sizedown=”false” text=”My Guardians vs Twins Prediction” center=”true” logo1url=”https://assets.actionnetwork.com/91388_guardians20241.png” link1=”https://www.actionnetwork.com/mlb/odds/cleveland-guardians” link1follow=”true” logo2url=”https://static.sprtactn.co/teamlogos/mlb/100/mind.png” link2=”https://www.actionnetwork.com/mlb/odds/minnesota-twins” link2follow=”true”][/subheader]
- Guardians vs Twins Picks: Under 7.5
My Guardians vs Twins best bet is Under 7.5. Make sure to find the best odds by checking our live MLB odds page.
_InlineAdBlock
Guardians vs Twins Odds, Run Line and Total
[gamematchup league=”mlb” awaylogo=”https://assets.actionnetwork.com/91388_guardians20241.png” awayname=”Guardians” awayslug=”cleveland-guardians” homelogo=”https://static.sprtactn.co/teamlogos/mlb/100/mind.png” homename=”Twins” homeslug=”minnesota-twins” date=”May 19, 2025″ time=”7:40 p.m. EDT” network=”CLEG” col1text=”Spread” col2text=”Total” col3text=”Moneyline” col1awaytext=”+1.5″ col1awayline=”-185″ col1hometext=”-1.5″ col1homeline=”+155″ col2awaytext=”7.5″ col2hometext=”7.5″ col2awayline=”-110o / -110u” col2homeline=”-110o / -110u” col3awaytext=”+120″ col3hometext=”-145″ col3awayline=”” col3homeline=”” bookname=”BetMGM” bookthumbnaillogo=”https://assets.actionnetwork.com/902516_MGM2.png” bookreviewslug=”betmgm”][/gamematchup]
[playercomparison league=”mlb” date=”20250519″ title=”Guardians vs Twins Probable Pitchers” awayplayerid=”147515″ awayplayerdisplay=”Logan Allen (CLE)” homeplayerid=”128169″ homeplayerdisplay=”Bailey Ober (MIN)” stattype=”pitching”][/playercomparison]
William Boor’s Guardians vs Twins Prediction and Pick
When wind blows in between 5-25 mph, fly balls lose carry and home run rates drop significantly, which obviously limits scoring. This system taps into that and targets games in which the total is set between 6-11.
Tonight’s Guardians vs. Twins matchup falls into those parameters, providing us with a sharp, weather-based angle that exploits the aforementioned environmental factors.
Pick: Under 7.5
Moneyline
I’m going to pass on the Guardians vs. Twins moneyline.
Run Line (Spread)
I don’t have a play for the Guardians vs. Twins run line.
Over/Under
I’m betting the Guardians vs. Twins under.
Guardians vs Twins Betting Trends
[bettingtrends title=”” gameid=”253864″ date=”20250519″][/bettingtrends]
[howtowatch gameid=”253864″ date=”20250519″][/howtowatch]
[subheader sizedown=”true” text=”Guardians vs Twins Weather” center=”false”][/subheader]
[gameforecast league=”mlb” gameid=”253864″ date=”20250519″][/gameforecast]
[procard imageurl=”https://assets.actionnetwork.com/736824_ActionPRO_promo_1500x844.jpg” cta=”Premium picks, tools & analysis” firstupsell=”Track & follow smart money” secondupsell=”Biggest player prop edges” thirdupsell=”Real-time expert pick alerts” buttontext=”SAVE 66% NOW!” buttonurl=”/pricing”][/procard]