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Guardians vs Tigers Prediction, Pick, Odds for Friday, May 23

The Detroit Tigers host the Cleveland Guardians on Friday, May 23, 2025. First pitch from Comerica Park is scheduled for 7:10 p.m. ET; the game will be broadcast on FanDuel Sports Detroit and Guardians TV.

This AL Central clash continues on Friday night — find our Guardians vs Tigers prediction below, as well as probable pitchers, betting trends and more.

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  • Guardians vs Tigers pick: Under 9

Our Guardians vs Tigers best bet for Friday is the game total under 9. Make sure to find the best odds by checking our live MLB odds page.


Guardians vs Tigers Odds

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Guardians vs Tigers Projected Starting Pitchers

RHP Slade Cecconi (CLE) Stat RHP Jackson Jobe (DET)
0-1 W-L 4-0
0.1 fWAR (FanGraphs) 0.0
5.40 / 3.47 ERA /xERA 4.12 / 4.45
2.48 / 1.33 FIP / xFIP 5.19 / 4.90
1.00 WHIP 1.45
40% K-BB% 5.8%
33.3% GB% 44.4%
99 Stuff+ 109
113 Location+ 96

Guardians vs Tigers Preview, Prediction

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Almost through the month of May, the AL Central is once again tightly congested with the Guardians, Twins and Royals sitting five games behind the first-place Tigers entering Friday.

The Guardians shut out the Tigers in the series opener on Thursday, with Tanner Bibeee dominating for seven innings before the bullpen shut the door.

Taking the hill for the Guardians on Friday is right-hander Slade Cecconi, who Cleveland acquired over the offseason in the Josh Naylor trade. Cecconi struck out eight over five innings of three-run ball in his season debut against the Reds.

The Tigers will counter with Jackson Jobe, who is a perfect 4-0 on the season — though his advanced metrics don’t back up the record.


Guardians vs Tigers Prediction, Betting Analysis

This system targets unders in MLB series games (Game 2 or later) where both teams have winning records, suggesting quality pitching and competitive matchups.

However, public betting leans toward the over — likely expecting fireworks between top teams — which creates contrarian value on the under.

By capitalizing on low public support for the under (≤35%), the strategy fades public perception in favor of market inefficiencies, especially when bettors overestimate offensive output late in a series.

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Pick: Under 9

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Moneyline

We have no bet on the moneyline.


Run Line (Spread)

We have no bet the game spread.


Over/Under

Our bet for this game is Under 9.


Guardians vs Tigers Betting Trends

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[gameforecast league=”mlb” gameid=”254029″ date=”20250523″][/gameforecast]


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