The Detroit Tigers (42-23) host the Chicago Cubs (39-24) on Saturday, June 7, 2025. First pitch from Comerica Park is scheduled for 1:10 p.m. ET; the game will be broadcast on MLB Network.
After riding Tarik Skubal to victory in the series opener of this interleague clash, the Tigers go for the series win on Saturday.
Find my Cubs vs Tigers prediction and moneyline pick for Saturday below, as well as probable pitchers, betting trends and more.
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- Cubs vs Tigers pick: Cubs moneyline (-108 | Play to -115)
My Cubs vs Tigers best bet for Saturday is the Cubs moneyline. Make sure to find the best odds by checking our live MLB odds page.
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Chicago Cubs vs Detroit Tigers Odds, Lines
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Cubs vs Tigers Projected Starting Pitchers
| RHP Jameson Taillon (CHC) | Stat | RHP Keider Monero (DET) |
|---|---|---|
| 5-3 | W-L | 2-1 |
| 0.1 | fWAR (FanGraphs) | 0 |
| 3.76 / 3.99 | ERA /xERA | 4.02 / 4.30 |
| 5.11 / 4.00 | FIP / xFIP | 4.74 / 4.70 |
| 1.01 | WHIP | 1.46 |
| 14.5% | K-BB% | 5.7% |
| 37.6% | GB% | 44.6% |
| 98 | Stuff+ | 95 |
| 111 | Location+ | 96 |
Cubs vs Tigers Preview, Prediction
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Following one of the best seasons of his career in 2024, Jameson Taillon has gotten off to a strong start in 2025. Through 12 starts, the right-hander is 5-3 with a 3.76 ERA and 1.01 WHIP.
He also ranks in the top half of the league in average exit velocity, walk rate and hard-hit rate. Following Taillon is a bullpen that has been in solid form recently.
Entering this matchup, Chicago’s relief staff ranks in the top half of the league in ERA, fielding independent pitching (FIP) and wins above replacement (WAR). This pitching staff should also benefit from plenty of run support.
The Cubs lead the league in both runs per game and hits per game. That success is likely to continue against Keider Montero.
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Montero trails Taillon in nearly every key category. Through eight appearances, the right-hander owns a 4.02 ERA and 1.46 WHIP.
His underlying metrics suggest that positive regression is unlikely. Montero ranks in the bottom third of the league in expected ERA (xERA), expected batting average (xBA) and strikeout rate.
Meanwhile, Detroit’s offense has been respectable this season. That said, it is still at a disadvantage in this matchup, particularly when compared to Chicago’s.
The Cubs outrank the Tigers in runs per game, hits per game, slugging percentage and OPS. There’s also a significant disparity on the basepaths: Chicago ranks second in stolen bases, while Detroit ranks 30th.
Cubs vs Tigers Prediction, Betting Analysis
The only edge the Tigers appear to hold is home-field advantage. However, that alone doesn’t justify the pick ’em price.
The Cubs have the superior starting pitcher, bullpen and lineup. They have also won each of Taillon’s past three starts.
Pick: Cubs moneyline (-108 | Play to -115)
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Moneyline
As mentioned, I’m betting on the Cubs moneyline.
Run Line (Spread)
I also like Chicago to cover, but find more value in just taking the outright moneyline price.
Over/Under
I lean toward the Over, but I don’t want to fade Taillon.
Cubs vs Tigers Betting Trends
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