red-sox-vs-tigers-prediction-pick-odds Pictured: Tarik Skubal

Red Sox vs Tigers Prediction, Odds, Pick, MLB Betting Guide

The Detroit Tigers host the Boston Red Sox on May 14, 2025. First pitch from Comerica Park is scheduled for 6:40 p.m. ET; the game will be broadcast on NESN and MLB.TV.

The Tigers enter as -250 favorites on the moneyline with the over/under sitting at 7.

Find my Red Sox vs Tigers prediction and MLB betting preview below, as well as probable pitchers, betting trends, injury reports and more.

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  • Red Sox vs Tigers Pick: Under 7 (+105)

My Tigers vs. Red Sox best bet is a play on the total — Under 7 (+105 at bet365). Make sure to find the best odds by checking our live MLB odds page.

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Red Sox vs Tigers Odds, Lines, Spread

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[playercomparison league=”mlb” date=”20250514″ title=”Red Sox vs Tigers Projected Pitchers” awayplayerid=”298252″ awayplayerdisplay=”Hunter Dobbins (BOS)” homeplayerid=”123018″ homeplayerdisplay=”Tarik Skubal (DET)” stattype=”pitching”][/playercomparison]

Red Sox vs Tigers MLB Betting Preview

Simply backing Tarik Skubal is one reason to bet an under, but it’s always nice when we have additional data to support a pick.

In this case, the weather also suggests a play on the under. So, let’s dig into the Bet Labs’ system.

When wind blows in between 5-35 mph, fly balls lose carry and home run rates drop significantly. As a result, this system targets unders when the wind is blowing in and the over/under is set between six and 11.

It’s a sharp, weather-based angle that exploits environmental factors that are often underweighted, but that heavily impact scoring outcomes.

Pick: Under 7


Red Sox vs Tigers Betting Trends to Know

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Red Sox vs Tigers starts at 6:40 p.m. EDT on Wednesday, live from Comerica Park. The game will be broadcast on NESN.


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