nfl-odds-sunday-bills-vs-bears-pick-prediction-8-17-2025

NFL Picks & Predictions for Bills vs Bears (Sunday, August 17)

The second game of Sunday’s NFL preseason doubleheader pits the Buffalo Bills against the Chicago Bears (8 p.m. ET, FOX).

When it comes to finding value, betting percentages and line moves create one of the more intriguing picks for NFL Sunday.

The top NFL pick for Bills vs. Bears using PRO insights is a contrarian prediction. Systems find fading the public is ideal for NFL preseason Sunday picks.

Bills vs. Bears carries added intrigue as second-year quarterback Caleb Williams makes his preseason debut under new head coach Ben Johnson.

Bettors have been actively moving lines since the opener, with Chicago initially favored by 1.5 points.

That spread has since shifted up to -2.5, while the total set at 41.5 remains one of the highest totals for any Week 2 preseason contest.

Last week, Chicago tied their preseason opener while Buffalo suffered a loss to the Giants, setting the stage for an interesting Sunday clash.

Looking for a pick on Sunday’s game? Let me introduce you to a contrarian model in Bet Labs which has predicted the winner against the spread in these situations at an excellent clip.

NFL Pick for Bills vs. Bears

There’s a side Sunday for Bills vs. Bears, which has only covered the point spread 42.8% of the time based on past, similar situations. Buyer beware!

Subscribers to PRO gain exclusive access to all types of proprietary, backtested trends and data-driven betting systems, and that includes the NFL preseason.

One system in particular is active Sunday on the Buffalo-Chicago game: The NFL preseason “Contrarian Sharp” model, which shines a light on the Chicago Bears to cover the spread.

This model highlights undervalued sides where the market hasn’t fully corrected after subtle line movements. It specifically targets preseason games where a team’s attracting less than 41% of the tickets we track, and the spread moves lightly, typically between -0.5 and -3.5 points.

Sunday’s Bears-Bills matchup fits this profile perfectly. Chicago opened -1.5 and moved to -2.5 despite receiving just 19% of spread tickets we log, indicating sharp money backing the Bears. In preseason games, controlled reverse line movements like this often signify sharper knowledge, such as coaching decisions or roster assessments not yet fully reflected in the market.

The ~57%-winning trend points to Caleb Williams and the Bears covering the point spread Sunday.

[quickslipbasic bookname=”Fanatics” booklogo=”https://assets.actionnetwork.com/573837_FanaticsSportsbook20ALT.png” image=”https://images.actionnetwork.com/blog/2025/08/IMG_3500.jpeg” buttontext=”Instantly Back the Bears to Cover!” buttonlink=”https://www.scoresandodds.com/all/parlay?quickslip=1&onelink=/5kut/tmuigjy4?sharedBy=QS_0105&ref=10001″][/quickslipbasic]

[betlabsembed systemid=”1489179″ systemname=”NFL PRESEASON: Contrarian Sharp” leaguename=”nfl” filters=”%7B%22list%22%3A%5B%22the%20game%20is%20played%20during%20the%20Preseason%20season%22%2C%22the%20spread%20%25%20is%20between%200%25%20and%2041%25%22%2C%22the%20spread%20change%20from%20open%20to%20close%20is%20between%20-3.5%20and%20-0.5%22%5D%7D” amountwon=”$2,039″ record=”99-74-3″ winpct=”57%”][/betlabsembed]

PRO System Pick: Bears Against the Spread


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Our PRO signals flag far more great picks than our staff could author each day — that’s where Action AI comes in. Using generative AI, signals that hit a high grade threshold are written up into articles that are then vetted and edited by a human to help us get you all the sharp action. Read more about how it works here.


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