The San Francisco Giants host the Tampa Bay Rays on August 16, 2025. First pitch from Oracle Park is scheduled for 9:05 p.m. EDT; the game will be broadcast on FDSSUN.
Find my MLB betting preview and Rays vs Giants prediction below, as well as probable pitchers, betting trends, injury reports, and more.
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- Rays vs Giants picks: Rays moneyline +110
My Rays vs Giants best bet is on the Rays moneyline. Make sure to find the best odds by checking our live MLB odds page.
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Rays vs Giants Odds
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Rays vs Giants Spread: Rays -1.5 (+164); Giants +1.5 (-203)
Rays vs Giants Totals: 8 (O -104 / U -116)
Rays vs Giants Moneyline: Rays -101; Giants -121
Rays vs Giants Best Bet: Rays ML
Rays vs Giants Projected Starting Pitchers
| Adrian Houser (TBR) | Stat | Justin Verlander (SFG) |
|---|---|---|
| 6-4 | W-L | 1-9 |
| 1.6 | fWAR (FanGraphs) | 0.9 |
| 2.84/4.46 | ERA /xERA | 4.53/4.70 |
| 3.74/4.41 | FIP / xFIP | 4.17/4.71 |
| 1.32 | WHIP | 1.50 |
| 8.5 | K-BB% | 11.5 |
| 47.7 | GB% | 34.2 |
| 90 | Stuff+ | 104 |
| 105 | Location+ | 93 |
Rays vs. Giants Prediction, Betting Analysis
In Major League Baseball betting, one of the most overlooked trends is backing road underdogs in interleague games. Since 2016, these teams have posted just a 43.3% win rate, yet they’ve delivered a +4.6% ROI—a rare edge that has held up across five straight profitable seasons.
This pattern highlights a market inefficiency in how oddsmakers and the public price interleague matchups. With limited familiarity between leagues and heavy bias toward home favorites, sportsbooks tend to undervalue road underdogs in these spots. For bettors, this creates a consistently profitable opportunity to target MLB moneyline underdogs where perception doesn’t match reality.
Pick: Rays ML
Moneyline
Back the Rays on the moneyline tonight.
Run Line (Spread)
There is no play on the run line.
Over/Under
There is no play on the total.
Rays vs Giants Betting Trends
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