The St. Louis Cardinals (54-53) and Miami Marlins (50-54) will face off in the MLB tonight. First pitch from Busch Stadium is scheduled for 7:45 p.m. ET. The game will broadcast live on FDSFL.
St. Louis is a -120 favorite to win outright on the moneyline, while Miami is +100 to pull off the upset. The over/under is set at 8 total runs.
Continue below for my Marlins vs Cardinals predictions and MLB picks for Monday, July 28, as well as probable pitchers, betting trends, injury reports and more.
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[subheader sizedown=”false” text=”My Marlins vs Cardinals Prediction” center=”true” logo1url=”https://static.sprtactn.co/teamlogos/mlb/100/mia_n.png” link1=”https://www.actionnetwork.com/mlb/odds/miami-marlins” link1follow=”true” logo2url=”https://static.sprtactn.co/teamlogos/mlb/100/stl.png” link2=”https://www.actionnetwork.com/mlb/odds/st.-louis-cardinals” link2follow=”true”][/subheader]
- Marlins vs Cardinals pick: Cardinals Moneyline (-120)
My Marlins vs Cardinals best bet is on St. Louis moneyline, with the best line currently available at DraftKings. But as always, make sure to find the best odds by checking our live MLB odds page.
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Marlins vs Cardinals Odds
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Marlins vs Cardinals Preview, Picks
When the Marlins open a series against a team coming off a game in the Eastern or Central time zone, the market often underrates the visiting opponent due to the perception of minimal travel impact, which appears to be the case heading into tonight’s matchup against the Cardinals.
In reality, these teams enter Game 1 with their routines intact and without the challenges of cross-country adjustments, allowing them to perform at expected or elevated levels.
Because the Marlins are not typically priced as a top-tier opponent, this creates value in fading them in the series opener.
This system capitalizes on that edge by betting against the Marlins in Game 1 during the regular or postseason when their opponent’s previous game was played in the Eastern or Central time zone, turning overlooked market assumptions into a profitable opportunity.
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Marlins vs Cardinals Best Bet
- Cardinals ML (-120)
Marlins vs Cardinals Betting Trends
[bettingtrends title=”” gameid=”258276″ date=”20250728″][/bettingtrends]
[howtowatch gameid=”258276″ date=”20250728″][/howtowatch]
[subheader sizedown=”true” text=”Marlins vs Cardinals Weather” center=”false”][/subheader]
[gameforecast league=”mlb” gameid=”258276″ date=”20250728″][/gameforecast]