The Cleveland Guardians (41-48) and Houston Astros (55-36) will face off in the MLB tonight. First pitch from Daikin Park is scheduled for 8:10 p.m. ET. The game will broadcast live on CLEG.
Houston is a -210 favorite to win outright on the moneyline, while Cleveland is +170 to pull off the upset. The over/under is set at 7 total runs.
Continue below for my Guardians vs Astros predictions and MLB picks for Tuesday, July 8, as well as probable pitchers, betting trends, injury reports and more.
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Guardians vs Astros Picks, Prediction
- Guardians vs Astros pick: Astros Moneyline (-210)
My Astros vs. Guardians best bet is on Houston moneyline, with the best line currently available at DraftKings. But as always, make sure to find the best odds by checking our live MLB odds page.
Guardians vs Astros Odds for Tuesday, July 8
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- Guardians vs Astros run line: Guardians +1.5 (-125), Astros -1.5 (+105)
- Guardians vs Astros over/under: 7 total runs
- Guardians vs Astros moneyline: Astros -210, Guardians +170
- Guardians vs Astros best bet: Astros ML (-210)
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Cleveland Guardians vs Houston Astros MLB Preview
This system identifies value in fading teams going up against elite starting pitchers, which the Guardians will do today.
It targets games where the opposing starter has a strong ERA (0 to 2.25), which may inflate their perceived edge, as is the case for Astros‘ starter Hunter Brown.
However, by backing teams with a slightly positive season-long margin (ATS margin avg 0.17 to 0.57), the system finds clubs that consistently exceed expectations.
Combined with a moneyline filter (-385 to -175), it focuses on favored teams who may be underpriced due to public fear of the opposing pitcher.
The edge lies in betting through the fog of that fear and backing the better team.
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Guardians vs Astros Betting Prediction
- Astros ML (-210)
Guardians vs Astros Betting Trends
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[gameinjuries league=”mlb” gameid=”257532″ date=”20250708″ week=”” seasontype=””][/gameinjuries]