The San Diego Padres host the Washington Nationals on June 25, 2025. First pitch from PETCO Park is scheduled for 4:10 p.m. EDT; the game will be broadcast on MASN2.
Find my Nationals vs Padres prediction and MLB player prop pick below.
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- Nationals vs Padres picks: Nick Pivetta Over 5.5 Strikeouts (-160)
My Nationals vs Padres best bet is Nick Pivetta Over 5.5 Strikeouts. Make sure to find the best odds by checking our live MLB odds page.
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Nationals vs Padres Odds
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Nationals vs Padres Projected Starting Pitchers
| LHP MacKenzie Gore (WAS) | Stat | RHP Nick Pivetta (SD) |
|---|---|---|
| 3-7 | W-L | 7-2 |
| 2.6 | fWAR (FanGraphs) | 1.7 |
| 3.19/3.41 | ERA /xERA | 3.64/4.01 |
| 2.94/2.91 | FIP / xFIP | 3.51/3.68 |
| 1.19 | WHIP | 1.08 |
| 25.2 | K-BB% | 19.8 |
| 35.0 | GB% | 32.1 |
| 99 | Stuff+ | 96 |
| 104 | Location+ | 112 |
Nationals vs Padres Prediction, Pick
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On paper, this Nationals team does not stand out as a great strikeout matchup, but these Padres pitchers have had success racking up strikeouts.
I also like this split matchup for Pivetta. He has had more success striking out and generating whiffs against lefties, as his CSW% is at 30% against lefties, but just 26.7% against righties.
That will be helpful, as there are six lefties in this projected Nationals lineup.
Pick: Nick Pivetta Over 5.5 Strikeouts (-160)
Nationals vs Padres Betting Trends
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[subheader sizedown=”true” text=”Nationals vs Padres Weather” center=”false”][/subheader]
[gameforecast league=”mlb” gameid=”257129″ date=”20250625″][/gameforecast]