The Houston Astros host the Philadelphia Phillies on Thursday, June 26, 2025. First pitch from Daikin Park is scheduled for 2:10 p.m. ET; the game will be broadcast on SCHN and MLB.TV.
The Astros enter as -150 favorites on the moneyline, while the Phillies sit at +123 to pull off the upset. The over/under, meanwhile, sits at 7.
Read our Phillies vs Astros prediction and MLB same-game parlay picks below.
[quickslipbasic bookname=”DraftKings” booklogo=”https://assets.actionnetwork.com/128508_Primary1.png” image=”https://images.actionnetwork.com/blog/2025/06/PhiAstrosQS.jpg” buttontext=”Click Here to Bet This Parlay!” buttonlink=”https://switchboard.actionnetwork.com/v2/deeplink?deeplinkId[0]=ML1650475547&deeplinkId[1]=ML1649814971&context=qs-articles”][/quickslipbasic]
[subheader sizedown=”false” text=”Philadelphia Phillies vs Houston Astros Prediction, Picks” center=”true” logo1url=”https://static.sprtactn.co/teamlogos/mlb/100/phi.png” link1=”https://www.actionnetwork.com/mlb/odds/philadelphia-phillies” link1follow=”true” logo2url=”https://static.sprtactn.co/teamlogos/mlb/100/hou.png” link2=”https://www.actionnetwork.com/mlb/odds/houston-astros” link2follow=”true”][/subheader]
- Hunter Brown Over 6.5 Ks
- Astros ML
Parlay odds: +178 (DraftKings)
Phillies vs Astros Odds, Line, Spread
[gamematchup league=”mlb” awaylogo=”https://static.sprtactn.co/teamlogos/mlb/100/phi.png” awayname=”Phillies” awayslug=”philadelphia-phillies” homelogo=”https://static.sprtactn.co/teamlogos/mlb/100/hou.png” homename=”Astros” homeslug=”houston-astros” date=”Thursday, June 26″ time=”2:10 p.m. ET” network=”MLB.TV” col1text=”Run Line” col2text=”Over/Under” col3text=”Moneyline” col1awaytext=”+1.5″ col1awayline=”-197″ col1hometext=”-1.5″ col1homeline=”+160″ col2awaytext=”7″ col2hometext=”7″ col2awayline=”-120o / -101u” col2homeline=”-120o / -101u” col3awaytext=”+123″ col3hometext=”-150″ col3awayline=”” col3homeline=”” bookname=”DraftKings” bookthumbnaillogo=”https://assets.actionnetwork.com/364880_Draftkings.png” bookreviewslug=”draftkings”][/gamematchup]
_InlineAdBlock
Phillies vs Astros Pitchers
LHP Cristopher Sanchez (PHI) | Stat | RHP Hunter Brown (HOU) |
---|---|---|
6-2 | W-L | 8-3 |
2.0 | fWAR (FanGraphs) | 2.5 |
2.87 / 3.31 | ERA / xERA | 1.88 / 3.04 |
3.14 / 3.13 | FIP / xFIP | 2.84 / 2.83 |
1.19 | WHIP | 0.92 |
17.6% | K-BB% | 23.5% |
55.7% | GB% | 46.8% |
113 | Stuff+ | 110 |
95 | Location+ | 98 |
Phillies vs Astros MLB Betting Preview
[subheader sizedown=”true” center=”false” text=”Astros Player Prop: Hunter Brown Over 6.5 Strikeouts” logo1url=”https://static.sprtactn.co/teamlogos/mlb/100/hou.png” link1=”https://www.actionnetwork.com/mlb/odds/houston-astros” link1follow=“false”][/subheader]
I’m backing young ace Hunter Brown to stay hot as he takes the mound.
Brown has been excellent all season. He sports a 1.88 ERA, 109 strikeouts, and an 8-3 record. If it weren’t for Skubal’s dominance, Brown could be a sneaky Cy Young candidate this season. He also boasts an outstanding whiff rate.
Specifically, I’m backing him to eclipse 6.5 strikeouts today against the Phillies.
The Phillies’ bats have struggled in Houston, with zero runs in 18 innings so far.
It won’t get any easier against Brown.
[subheader sizedown=”true” center=”false” text=”Moneyline Pick: Astros ML” logo1url=”https://static.sprtactn.co/teamlogos/mlb/100/hou.png” link1=”https://www.actionnetwork.com/mlb/odds/houston-astros” link1follow=“false”][/subheader]
In addition, I’m betting on the Astros to complete the sweep.
Houston has been playing good baseball, going 4-1 over its past five games.
At home with its ace on the mound, you have to back the hot team. I expect the Astros will pull out a low-scoring victory on Thursday.
Phillies vs Astros MLB Same-Game Parlay Picks
- Hunter Brown Over 6.5 Ks
- Astros ML
Parlay odds: +178 (DraftKings)
[procard imageurl=”https://assets.actionnetwork.com/736824_ActionPRO_promo_1500x844.jpg” cta=”Premium picks, tools & analysis” firstupsell=”Track & follow smart money” secondupsell=”Biggest player prop edges” thirdupsell=”Real-time expert pick alerts” buttontext=”SAVE 66% NOW!” buttonurl=”/pricing”][/procard]
Phillies vs Astros Betting Trends to Watch
[bettingtrends title=”” gameid=”257163″ date=”20250626″][/bettingtrends]
[subheader sizedown=”true” text=”Phillies vs Astros Weather Forecast” center=”false”][/subheader]
[gameforecast league=”mlb” gameid=”257163″ date=”20250626″][/gameforecast]
_InlineAdBlock