As we dive into the best MLB model picks for Sunday, two key matchups stand out to PRO Systems: the Chicago White Sox vs. Toronto Blue Jays and the Arizona Diamondbacks vs. Colorado Rockies.
Our proprietary betting trends and situational angles are actively signaling strong edges on both games, giving subscribers powerful insights to capitalize on. PRO subscribers get full access to these sophisticated, backtested trends and can build endless situational models using Bet Labs.
Check out two neat moneyline predictions for Sunday afternoon MLB. First pitches are 1:37 p.m. ET and 3:10 p.m. ET.
MLB Sunday, June 22: Picks for White Sox vs Blue Jays, Diamondbacks vs Rockies
Starting with the White Sox vs. Blue Jays, Toronto (-210) looks poised to continue its strong run after a dominant 7-1 win on Saturday.
The Hot Teams vs. Ice-Cold Opponents PRO System is firmly backing Toronto here. This system targets teams deep into the MLB season (games 6–158) that are gaining momentum while facing opponents in clear decline. Specifically, it isolates matchups where the opponent boasts one of the worst win rates in baseball (between 1–33%), is on a losing streak, and where the favored team is coming off a win.
Coupled with a moneyline range of moderate-to-heavy favoritism (-375 to -140), this system leverages a potent combination of short-term momentum and long-term weakness to identify undervalued favorites against floundering opponents.
It’s a match on the Blue Jays and a big fade of the White Sox.
PRO Pick: Blue Jays Moneyline
Transitioning to the Diamondbacks-Rockies game, the PRO System “Fading the Flawed: Road Faves with Risk” is active, with a proven 71% hit rate since tracking started. This model targets road favorites whose starting pitchers have elevated ERA (4.56 to 53.7) and WHIP (1.36 to 10.45), indicating below-average performance. Despite these warning signs, the market prices these teams between -225 and -150, often overestimating their chances.
Here, the system advises fading the team due to overvaluation driven by reputation rather than actual pitching effectiveness. Since 2020, this approach has isolated inefficiencies in the betting markets surrounding road favorites with shaky arms.
Despite Brandon Pfaadt’s recent struggles, PRO Systems lends an edge to the Diamondbacks.
PRO Pick: Diamondbacks Moneyline
In summary, Sunday’s PRO Systems point to betting on two big favorites: the Jays over the White Sox and laying the chalk on Arizona against Colorado.
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