The UCLA Bruins face the LSU Tigers in the 2025 Men’s College World Series. First pitch is set for 7 p.m. ET on ESPN.
LSU enters as a big -315 favorite on the moneyline with the over/under sitting at 9.5. The run line, meanwhile, sits at LSU -2.5 (-115).
Let’s dive into our UCLA vs. LSU prediction and NCAA baseball picks for the College World Series on Monday, June 16.
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UCLA vs LSU Prediction
- UCLA vs. LSU Pick: LSU -2.5 (+105)
My LSU vs. UCLA best bet is on the Tigers to cover the run line, with the best line currently available at BetRivers.
UCLA vs LSU Odds
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- UCLA vs LSU Moneyline: UCLA +230 · LSU -315
- UCLA vs LSU Over/Under: 9.5 Runs
- UCLA vs LSU Run Line: LSU -2.5 (-115) · UCLA +2.5 (-115)
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The LSU Tigers are sitting pretty in the winners’ bracket as everything has gone to plan thus far. They only needed to use two arms in an upset win over Arkansas, and they now get to throw another stud in Anthony Eyanson tonight.
Anderson may get more buzz, but Eyanson can be just as dominant. He pitched to a 2.74 ERA and 1.14 WHIP this season while averaging 13 strikeouts per nine innings.
What’s great for us is that he’s shown no signs of regression, so he’s the guy to back against a UCLA lineup that’s no joke in its own right.
However, the issue I’ve had with the Bruins throughout the postseason is their lack of pitching depth when having to contend with elite lineups. Tonight, they’ll start Ian May, who holds a 4.93 ERA over 69 1/3 innings of work.
May has been solid recently, but he hasn’t faced a lineup like LSU’s. The Tigers can mash, as they ranked eighth in wRC+ and 31st in OPS this season.
As for May, he pitches to contact. He averages only 6.1 strikeouts per nine innings, and all that contact allowed has him in line for regression. May’s xFIP of 5.89 and SIERA of 4.63 show he’s due to be knocked around against an elite lineup.
With Eyanson on the mound of the Tigers and plenty of run support expected, back LSU to cover the run line as it improves to 2-0 in Omaha.
Pick: LSU -2.5 (+105)
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