The Houston Astros host the Chicago White Sox on June 12, 2025. First pitch from Daikin Park is scheduled for 8:10 p.m. EDT; the game will be broadcast on SCHN.
Find my MLB betting preview and White Sox vs Astros prediction below, as well as probable pitchers, betting trends, injury reports and more.
White Sox vs Astros Odds
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- White Sox vs Astros pick: Jose Altuve Over 0.5 Home Runs (+750)
My White Sox vs Astros best bet is to back Jose Altuve to homer. Make sure to find the best odds by checking our live MLB odds page.
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Alex Kolodziej’s White Sox vs Astros Prediction, Betting Pick
Today is a good day to bet Jose Altuve to hit a home run against the White Sox.
As I personally monitor PRO home run projections every day, Altuve is a hitter who, despite average power numbers, seems to make the cut whenever the price is right.
Thursday’s odds list Altuve at +800 to hit a home run. With Action PRO models at 0.17 home runs for Altuve, our home run models expect a +4.5% edge over the market.
Altuve has nine home runs. He bats high in the order, has an ideal swing path for homers and benefits from a short porch in left field.
FanDuel offers the best price at +800, while other shops are as low as +750.
Pick: Jose Altuve Over 0.5 Home Runs (+750)
Moneyline
I’m going to pass on the White Sox vs. Astros moneyline.
Run Line (Spread)
I’m not betting the White Sox vs. Astros run line.
Over/Under
I have no play on the White Sox vs. Astros over/under.
White Sox vs Astros Betting Trends
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[howtowatch gameid=”256374″ date=”20250612″][/howtowatch]
White Sox vs Astros starts at 8:10 p.m. EDT on Thursday, live from Daikin Park. The game will be broadcast on SCHN.
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[gameforecast league=”mlb” gameid=”256374″ date=”20250612″][/gameforecast]
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