Dodgers vs Cardinals Prediction, Props, Picks, Odds

The St. Louis Cardinals (34-28) host the Los Angeles Dodgers (38-25) on Friday, June 6, 2025. First pitch from Busch Stadium is scheduled for 8:15 p.m. ET; the game will be broadcast on SportsNet LA and FanDuel Sports Midwest.

The Dodgers enter Friday night as rare underdogs, coming in at -101 on the moneyline while the Cardinals are -121 favorites. The game total is set at 8.5

Find my Dodgers vs. Cardinals prediction and prop pick for the Friday series opener below.

[quickslipbasic bookname=”BetMGM” booklogo=”https://assets.actionnetwork.com/779359_BetMGM800x200@1x.png” image=”https://images.actionnetwork.com/blog/2025/06/Screenshot-2025-06-06-at-12.46.22-PM.png” buttontext=”Instantly Add Ohtani Double to Bet Slip!” buttonlink=”https://switchboard.actionnetwork.com/v2/deeplink?deeplinkId[0]=ML1613817616&context=qs-articles”][/quickslipbasic]

[subheader sizedown=”false” text=”Dodgers vs Cardinals Prediction, Props, Picks” center=”true” logo1url=”https://static.sprtactn.co/teamlogos/mlb/100/ladd.png” link1=”https://www.actionnetwork.com/mlb/odds/los-angeles-dodgers” link1follow=”true” logo2url=”https://static.sprtactn.co/teamlogos/mlb/100/stl.png” link2=”https://www.actionnetwork.com/mlb/odds/st.-louis-cardinals” link2follow=”true”][/subheader]

• Dodgers vs Cardinals Pick: Shohei Ohtani Over 0.5 Doubles (+470)

My Cardinals vs. Dodgers best bet is on Los Angeles star Shohei Ohtani to hit a double. Make sure to find the best odds by checking our live MLB odds page.

Dodgers vs Cardinals Odds

[gamematchup league=”mlb” awaylogo=”https://static.sprtactn.co/teamlogos/mlb/100/ladd.png” awayname=”Dodgers” awayslug=”los-angeles-dodgers” homelogo=”https://static.sprtactn.co/teamlogos/mlb/100/stl.png” homename=”Cardinals” homeslug=”st.-louis-cardinals” date=”Friday, Jun 6″ time=”8:15 p.m. ET” network=”SportsNet LA” col1text=”Spread” col2text=”Total” col3text=”Moneyline” col1awaytext=”-1.5″ col1awayline=”+160″ col1hometext=”+1.5″ col1homeline=”-197″ col2awaytext=”8.5″ col2hometext=”8.5″ col2awayline=”-114o / -106u” col2homeline=”-114o / -106u” col3awaytext=”-101″ col3hometext=”-121″ col3awayline=”” col3homeline=”” bookname=”DraftKings” bookthumbnaillogo=”https://assets.actionnetwork.com/603379_Primary.png” bookreviewslug=”draftkings”][/gamematchup]

_InlineAdBlock

Dodgers vs Cardinals Preview, Prediction

[subheader sizedown=”true” center=”false” text=”Dodgers Player Props: How to Bet Shohei Ohtani” logo1url=”https://static.sprtactn.co/teamlogos/mlb/100/ladd.png” link1=”https://www.actionnetwork.com/mlb/odds/los-angeles-dodgers” link1follow=”false”][/subheader]

Watching Shohei Ohtani launch dingers into the troposphere doesn’t get old.

But for tonight’s upcoming Dodgers vs. Cardinals game, one of the top MLB betting opportunities identified by our PRO Projections is wagering on Ohtani to record a double.

As of writing, FanDuel offers odds of +470 for Ohtani to hit a double on Friday, making it an attractive play for bettors looking for value — and maybe a pivot off the home run market.

Entering Friday’s matchup, Ohtani has already hit 23 home runs this season but has surprisingly gone 12 consecutive games without a double.

Given his consistent power, hitting ability and slugging prowess, this suggests he might be primed to break that streak soon.

Dodgers vs Cardinals Pick, Betting Analysis

Our proprietary PRO Projection system forecasts Ohtani to hit approximately 0.28 doubles in this game.

This weekend’s series in St. Louis could be an ideal opportunity to capitalize on these odds. At home in Los Angeles, Ohtani typically benefits from one of Major League Baseball’s best home-run parks, but Busch Stadium in St. Louis ranks as one of the tougher environments for home runs.

Over the past three seasons, Busch Stadium has been ranked as the 10th-best park for doubles, yet the sixth-worst for home runs.

This makes the double bet one of the strongest edges identified by our PRO Projections tonight.

Pick: Shohei Ohtani Over 0.5 Doubles (+470)

[procard imageurl=”https://assets.actionnetwork.com/736824_ActionPRO_promo_1500x844.jpg” cta=”Premium picks, tools & analysis” firstupsell=”Track & follow smart money” secondupsell=”Biggest player prop edges” thirdupsell=”Real-time expert pick alerts” buttontext=”SAVE 66% NOW!” buttonurl=”/pricing”][/procard]

Dodgers vs Cardinals Betting Trends

[bettingtrends title=”” gameid=”256086″ date=”20250606″][/bettingtrends]

[subheader sizedown=”true” text=”Dodgers vs Cardinals Weather” center=”false”][/subheader]
[gameforecast league=”mlb” gameid=”256086″ date=”20250606″][/gameforecast]

_InlineAdBlock