The Pittsburgh Pirates host the Houston Astros on June 3, 2025. First pitch from PNC Park is scheduled for 6:40 p.m. ET; the game will be broadcast on SportsNet PT and MLB.TV.
The Pirates come into the game as -165 favorites, while the over/under sits at 7.5.
Find my Astros vs Pirates prediction and MLB betting preview below, as well as probable pitchers, betting trends, injury reports and more.
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- Pirates ML -160
- Alexander Canario Over 0.5 Hits
Parlay Odds: +138 (BetMGM)
Astros vs Pirates Odds, Line, Spread
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Astros vs Pirates Projected Pitchers
| Lance McCullers Jr. (HOU) | Stat | Paul Skenes (PIT) |
|---|---|---|
| 0-1 | W-L | 4-5 |
| 0.1 | fWAR (FanGraphs) | 2.3 |
| 5.89 / 4.57 | ERA /xERA | 2.15 / 2.47 |
| 4.66 / 3.79 | FIP / xFIP | 2.52 / 3.07 |
| 1.69 | WHIP | 0.92 |
| 16.5 | K-BB% | 20.1 |
| 43.1 | GB% | 49.5 |
| 102 | Stuff+ | 108 |
| 90 | Location+ | 110 |
Astros vs Pirates MLB Betting Preview
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This is the first of a three-game series between the Pirates and the Astros. The Pirates are 22-38 this year, including 13-16 at PNC Park.
But guess what: It’s Paul Skenes day. He takes the mound for the Pirates, and he’s always an electric watch.
The Astros are 32-27 this year, but they’re just 10-15 on the road.
The Pirates have won three of their last five, and their bats will lead Skenes to victory on Tuesday.
[subheader sizedown=”true” center=”false” text=”Pirates Player Prop: Alexander Canario Over 0.5 Hits” logo1url=”https://static.sprtactn.co/teamlogos/mlb/100/pit.png” link1=”https://www.actionnetwork.com/mlb/odds/pittsburgh-pirates” link1follow=“false”][/subheader]
Alexander Canario has been ice-cold this past week. He’s just 2-for-14 in the last seven days, but Tuesday is his day to bounce back.
Canario has been decent all season long versus right-handed pitchers and Tuesday is the day he breaks out of his slump.
Astros vs Pirates Betting Trends to Know
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