PRO Report is buzzing with actionable picks in the early morning MLB game.
The Cardinals vs. Reds game, the first on the card for MLB Wednesday, features sharp moneyline and over/under predictions in PRO.
The NL Central rivals play a doubleheader after last night’s game was rained out. Game 1’s first pitch is scheduled for 12:40, and that’s exactly the tilt we’re profiling below.
Miles Mikolas gets the start for the Cardinals, opposite Brady Singer. The Reds are favored at home Wednesday in Game 1, with a high total at Great American Ball Park.
Here’s how sharps are betting the moneyline and over/under.
MLB Odds: Cardinals vs Reds Moneyline, Over/Under Picks for Game 1
Sharp bettors have no problem laying the chalk on the Reds moneyline in the early game.
Cincinnati is catching smart bets in Bet Labs, and PRO backs it up, hinting that the home side’s been attracting action from influential bettors.
Singer, today’s starter for the Reds, is 4-0 with a 3.62 ERA this season. Beyond those peripherals, his StatCast metrics are excellent, ranking solid in stats like xERA (2.99) and xBA (.223).
Mikolas, meanwhile, has been roughed up early. He’s barely generating any whiffs and both his ERA (5.70) and xERA (4.73) are bleak.
The Reds are as long as -150, but our MLB odds page shows FanDuel with the best price (-142) on the moneyline.
[quickslipbasic bookname=”FanDuel” booklogo=”https://assets.actionnetwork.com/53766_FanDuel@1x.png” image=”https://images.actionnetwork.com/blog/2025/04/IMG_2123.jpeg” buttontext=”Tail the Reds Instantly!” buttonlink=”https://sharpside.com/books/fanduel/passthrough?deeplinkId[0]=ML1523351108&context=qs-articles”][/quickslipbasic]
Meanwhile, the Reds vs. Cardinals under is catching multiple big bets as first pitch gets near.
Bet Labs shows the under was bet several times. There was a bunch of resistance whenever the market hit 9.5 on the total, and shops like ESPN Bet are still hanging that number at the time of writing.