The Detroit Pistons (41-32) will host the Cleveland Cavaliers (59-14) in the NBA tonight. Tipoff is set for 7 p.m. ET from Little Caesars Arena in Detroit, Michigan. The game will broadcast live on NBA League Pass.
The Cavaliers are 6.5-point road favorites over the Pistons on the spread (Cavaliers -6.5), with the over/under set at 231.5 total points. Cleveland is a -260 favorite to win outright, while Detroit is +210 to pull off the upset.
Let’s get to my Cavaliers vs. Pistons predictions and NBA picks for Friday, March 28.
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Cavaliers vs Pistons Prediction, Picks
My Pistons vs. Cavaliers best bet is on Ausar Thompson Over 4.5 Rebounds, with the best line currently available at DraftKings. But as always, make sure to shop for the best line using our live NBA odds page.
My Pick: Ausar Thompson Over 4.5 Rebounds
Cavaliers vs Pistons Betting Odds
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- Cavaliers vs. Pistons spread: Cavaliers -6.5
- Cavaliers vs. Pistons over/under: 231.5 total points
- Cavaliers vs. Pistons moneyline: Pistons +210, Cavaliers -260
- Cavaliers vs. Pistons best bet: Ausar Thompson Over 4.5 Rebounds
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Cleveland Cavaliers vs Detroit Pistons NBA Preview
By Nick Galaida
Ausar Thompson should be in line for an expanded workload tonight, with the Pistons missing both Cade Cunningham and Jaden Ivey.
In three games with Cunningham and Ivey both inactive, Thompson has recorded two games of 6+ rebounds, with the lone exception being a game in which he was limited to nine minutes due to foul trouble. In the two games in which he played 20+ minutes in that sample, Thompson had 10 rebound chances and 9 rebound chances, respectively.
Overall this season, Thompson has secured 5+ rebounds in 23 of 31 games in which he’s played 20+ minutes, including 12 of 17 games at home. This is good value, given Detroit’s injury situation.
Best Bet: Ausar Thompson Over 4.5 Rebounds (-130)
Cavaliers vs Pistons Parlay Picks
I’m following the tea leaves here and betting on Donovan Mitchell potentially getting the night off for the Cavaliers after playing 35 minutes in yesterday’s win over the Spurs.
If that’s the case, this line is simply too low for Mobley, who has 3+ assists in each of the last six games he’s played in which Mitchell has been inactive.
According to RotoGrinders’ CourtIQ, Mobley is averaging 4.9 assists per 36 minutes with Mitchell off of the floor this season.
Even if Mitchell plays, Mobley should have a good chance to get 3+ assists. Entering play, he’s averaging 3.3 assists and 5.9 potential assists in 16 games since the All-Star Break.
Pick: Evan Mobley Over 2.5 Assists (-150)
Cavaliers vs Pistons Same Game Parlay
- Ausar Thompson Over 4.5 Rebounds
- Evan Mobley Over 2.5 Assists
Parlay Payout: +170
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Pistons vs Cavaliers Betting Trends
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[howtowatch gameid=”246621″ date=”20250328″][/howtowatch]