Our data shows four college football teams in particular on upset alert Saturday of Week 6.
Our proprietary analysis tools, PRO Projections and PRO Systems, identified four underdogs worth a wager. All four moneyline bets are listed at solid prices. Utilizing advanced college betting models, our picks have uncovered two potentially profitable underdogs, including an eye-catching +421 sleeper.
Furthermore, our insightful college football moneyline PRO System highlights key teams that have consistently emerged in closely contested games—providing a smart approach to betting this weekend.
College Football Upset Predictions and Moneyline Bets Saturday Week 6
Our exploration into upset picks for Week 6 begins with Kansas traveling to Arizona State.
Kansas’ moneyline stands is +115, conflicting sharply with PRO Projections, which favors Kansas at -117.
Also, Kansas is also supported by the “Small Visiting Dog” PRO System, a historically profitable betting trend with a 51% win rate.
Small underdogs with high totals are typically a good bet, and Kansas fits the mold in Week 6.
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PRO Prediction: Kansas Moneyline
The second upset pick from Small Visiting Dogs is Appalachian State making the trip to Marshall.
App State is catching 3 points on the road, with a high total. Our best bet is on the Mountaineers moneyline at +125.
PRO Prediction: Appalachian State Moneyline
Moving on, another upset pick from Small Visiting Dogs is West Virginia to trip up Oklahoma State.
Priced the same as Appalachian State, West Virginia sits at +125, and could be in a good spot to upend Oklahoma State off a big loss at K-State.
PRO Prediction: West Virginia Moneyline
Lastly, we turn to UAB facing an uphill battle against Tulane.
Our PRO Projections provide a significant edge here by re-evaluating the standard market moneyline of +600 for UAB, adjusting it to a more favorable +421 with a B-grade rating.
This sleeper pick, backed by our advanced models, spotlights another avenue for a potentially shocking victory on this action-packed Saturday.
PRO Prediction: UAB Moneyline
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Our PRO signals flag far more great picks than our staff could author each day — that’s where Action AI comes in. Using generative AI, signals that hit a high grade threshold are written up into articles that are then vetted and edited by a human to help us get you all the sharp action. Read more about how it works here.