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Commanders vs Cardinals Picks, Odds, Predictions for NFL Week 4

Commanders vs. Cardinals may take the cake as most entertaining NFL Week 4 game Sunday. To sweeten the pot, we’ve recorded a sharp over/under pick in PRO between two high-octane offenses.

The game kicks off at 4:05 p.m. ET, and both teams enter with identical 1-2 records.

Commanders’ QB Jayden Daniels and Cardinals’ QB Kyler Murray, both known for their dual-threat capabilities, highlight what should be an exhilarating matchup.

Oddsmakers have set the spread at Cardinals -3.5 and the over/under at 49. The moneyline odds currently favor the Cardinals at -175 with the Commanders set at +150.

Commanders vs. Cardinals Odds, Picks, Predictions

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  • Commanders vs. Cardinals spread: Cardinals -3.5
  • Commanders vs. Cardinals over/under: 49
  • Commanders vs. Cardinals moneyline: Commanders +150, Cardinals -178

Spread

Murray and the Cardinals are -3.5 at home.

Over/Under

The over/under is set at 49 points. Both teams’ over/unders have been set on the higher side this season.

Moneyline

The moneyline tabs the Cardinals as -178 favorites, while the Commanders are listed at +150 to pull off their second straight upset.

Player Prop

PRO Projections give Brian Robinson Jr. a 12% chance to score the first TD. His odds are +900, implying a 10% chance and offering a 2% edge on the Commanders RB to open the scoring.

PRO Projections recommend a 3.5% or better when tailing, so this one doesn’t exactly meet the criteria.

Commanders vs. Cardinals Prediction

A couple Action PRO models matching on the over/under sparks an almost-too-obvious prediction.

Point Spread

Key betting insights indicate some contrarian data points.

We’ve tracked sharp money coming in on the Commanders, with professional action backing the away team.

Moreover, a pertinent PRO System—”Road Dog, Low Total After Bad Season”—supports the Commanders, boasting a 58% win rate and a 14% ROI.

Interestingly, big money bets align differently, with the Cardinals receiving 69% of the money but only 43% of the bets.

[expertpickswidget league=”nfl” gameid=”227416″ date=”20240929″ week=”4″ seasontype=””][/expertpickswidget]

Total

The total over/under for this game is set at 49. Betting activity has shown sharp money overwhelmingly on the over.

Additionally, big money bets have also sided with the over, making up 68% of the total money and 52% of the bets. Both teams boast offensive playmakers in Daniels and Murray, and the overall betting landscape sees potential value in betting the over, suggesting a high-scoring affair may be likely in Glendale.

Odds to Win

Big money has notably landed on the Commanders, who have garnered 56% of the money and just 27% of the bets. This split indicates strong interest from sharp bettors in the Commanders potentially pulling off the upset.

Our PRO Pick

Given the extensive betting data and proprietary insights, our top recommendation hinges on over 49. The blend of sharp action and big money oriented towards the over makes this an enticing opportunity.

Commanders vs. Cardinals Betting Trends

  • The Cardinals have scored 82 total pts through three games, the 4th-most of any team in the NFL.
  • The Cardinals recently have started hot. They are .500 ATS or better in the first four games of the regular season in seven straight seasons, going 10-5 ATS since 2021 in that spot.

Commanders vs. Cardinals Weather

[gameforecast league=”nfl” gameid=”227416″ date=”20240929″][/gameforecast]


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Our PRO signals flag far more great picks than our staff could author each day — that’s where Action AI comes in. Using generative AI, signals that hit a high grade threshold are written up into articles that are then vetted and edited by a human to help us get you all the sharp action. Read more about how it works here.


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