college football odds murray state vs louisville - Louisville Cardinals head coach Jeff Brohm addresses the fans

College Football Odds for Murray State vs Louisville: Betting Prediction for Thursday

College Football Odds for Murray State vs Louisville

Murray State Odds +43.5
Louisville Odds -43.5
Over/Under 56.5 (-110 / -110)
Date Thursday, Sept. 7
Time 7:30 p.m. ET
Channel ACC Network

*College football odds as of Thursday morning

Thursday night football is back!

I’m sure most fans and bettors will be focusing on the NFL season-opening game between the Detroit Lions and Kansas City Chiefs tonight, but professional football isn’t the only game in town.

Murray State vs. Louisville will also take place on Thursday night, and the latest college football odds show the Cardinals as huge, and not at all surprising, 42.5-point favorites over the Racers.

While recreational bettors may avoid this matchup altogether to focus on Lions vs. Chiefs, wiseguys are already shaping Murray State vs Louisville odds.

Let’s take a look at the college football prediction that pros are making for Murray State vs Louisville.

College Football Prediction for Murray State vs Louisville

As mentioned above, Louisville currently sits at -42.5 at most sportsbooks.

However, this line actually opened at -40.5, suggesting that savvy bettors were not scared off by laying the huge number.

Action Labs’ Bet Signals concur, reporting that sharps steamed the Cardinals at -40.5, confirming why this spread has increased two points (click here for live college football odds).

Steam refers to sudden, uniform line movement across the market that is often the result of bettors with the resources and respect to move odds getting down on the same side of the same game at multiple sportsbooks all at once.

This game may attract very little action from casual bettors, though wiseguys aren’t letting that stop them from finding value.

PRO Report Prediction: Louisville -42.5

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